Research

May 28, 2020

Seeking a regenerative therapy for chronic dry mouth

By Susan Buckles Susan Buckles

Mayo Clinic researchers are seeking a regenerative therapy for a vexing problem, particularly among cancer patients. How can medical providers treat a condition in which the mouth is so parched that it has an incessant feeling of a cotton lining? Xerostomia, also known as chronic dry mouth, is an agonizing side effect of injury to […]

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Tags: #Dr. Jeffrey Janus, #Dr. Nagarajan Kannan, #Dry mouth, #epithelial cells, #Mayo Clinic Center for Regenerative Medicine, #stem cell research, #xerostomia


May 14, 2020

Research grants aim to advance regenerative medicine toward the practice

By Susan Buckles Susan Buckles

Reprogramming human cells to correct blood disorders such as sickle cell disease, activation of a regenerative pathway to treat liver failure and strategies for skeletal regeneration in patients with brittle bone disease are examples of Mayo Clinic research to be funded through new grants from Regenerative Medicine Minnesota.  Regenerative Medicine Minnesota, a statewide bipartisan initiative, […]

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Tags: #Dr. David Deyle, #Dr. Patricia Devaux, #Dr. Steven Moran, #Dr. Terry Burns, #Mayo Clinic Center for Regenerative Medicine, #Regenerative Medicine Minnesota, #Rory Smoot, Dr. Dan Dragomir-Daescu, Dr. Martin Rodriguez-Porcel


May 7, 2020

A discovery step toward cell replacement therapy for diabetes

By Susan Buckles Susan Buckles

In what could be a step toward cell replacement therapy for diabetes, Mayo Clinic researchers have discovered how to manufacture cells capable of generating a hormone that regulates low blood sugar. Quinn Peterson, Ph.D. and his team have developed a new method of mass producing a cell product containing the hormone glucagon that is capable […]

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Tags: #Biomanufacturing, #cell replacement therapy, #Diabetes, #Dr. Quinn Peterson, #hypoglycemia, #Mayo Clinic Center for Regenerative Medicine, #stem cells


April 16, 2020

Focus on women’s health: regenerative approaches to stress and fecal incontinence

By Susan Buckles Susan Buckles

Mayo Clinic is taking a regenerative approach to women’s healthcare to provide new therapeutic options for common conditions that standard treatments don’t fully address. One key area of focus is pelvic floor injury that leads to stress incontinence, a widespread and often embarrassing problem affecting some 18 million women, according to the National Association for […]

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Tags: #Dr. Emanuel Trabuco, #fecal incontinence, #incontinence, #Mayo Clinic Center for Regenerative Medicine, #urinary incontinence


April 9, 2020

Transforming the future of organ transplantation

By Susan Buckles Susan Buckles

Mayo Clinic is turning to regenerative medicine to address a critical shortage of donor organs. Physicians and scientists are studying 3D printing, tissue engineering and cellular and cell free therapies as ways to build new organs or restore the health of organs that previously were discarded. The ultimate goal is to provide a transplant for […]

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Tags: #Dr. C. Burcin Taner, #Dr. Dennis Wigle, #Mayo Clinic Center for Regenerative Medicine, #Organ Transplants, Mayo Clinic Florida


April 1, 2020

Mayo Clinic research finds spina bifida surgery before birth restores brain structure

By Susan Buckles Susan Buckles

Surgery performed on a fetus in the womb to repair defects from spina bifida triggers the body’s ability to restore normal brain structure, Mayo Clinic research discovered. Research by Rodrigo Ruano, M.D., Ph.D., chair of Mayo Clinic’s Division of Maternal and Fetal Medicine, finds that fetal surgery to correct congenital spinal cord defects is more […]

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Tags: #Brain regeneration, #Fetal surgery research, #hydrocephalus, #Mayo Clinic Proceedings, #Myelomeningocele, #Spina Bifida, Dr. Rodrigo Ruano, fetal surgery, Mayo Clinic Center for Regenerative Medicine


March 19, 2020

Regenerating diseased bones

By Susan Buckles Susan Buckles

Kendall Koens’ life is a dramatic reversal from what it was in 2006. Late stage cancer left him in a coma and on a ventilator fighting for survival. Aggressive chemotherapy was saving his life but slowly and silently destroying his hips joints. The financial planner from Rochester faced crippling pain typical of someone more than […]

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Tags: #Avascular hip necrosis, #Dr. Rafael Sierra, #hip replacement, #osteonecrosis, arthritis, cancer, Mayo Clinic Center for Regenerative Medicine


Mayo Clinic research discovers how stem cells repair damage from heart attacks

March 12, 2020

Mayo Clinic research discovers how stem cells repair damage from heart attacks

By Susan Buckles Susan Buckles

Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins […]

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Tags: #Dr. Kent Arrell, #heart failury, cardiovascular disease, Cariopoietic stem cells, Dr. Andre Terzic, heart attack, Mayo Clinic Center for Regenerative Medicine, mesenchymal stem cells


March 6, 2020

Improving remyelination for spinal cord injury: Arthur Warrington, Ph.D.

By Jennifer Schutz Jennifer Schutz

Mayo Clinic researchers are probing potential ways to unleash the human body’s ability to heal neurological disorders like spinal cord injuries or multiple sclerosis. Myelin is the protective covering that surrounds nerve fibers in the brain, optic nerves and spinal cord. Demyelination, or injury to the myelin, slows electrical signals between brain cells, resulting in […]

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Tags: Arthur Warrington, MS, multiple sclerosis, Neurology, regenerative medicine, spinal cord injury


February 20, 2020

Patient consults: finding the best treatment option for each individual

By Susan Buckles Susan Buckles

Is regenerative medicine in your future or would standard procedures be the best remedy for diseases like arthritis? Mayo Clinic’s Regenerative Medicine Consult Service helped two men with a similar disease choose two vastly different paths to healing based on their individual conditions and lifestyles. 79-year old Joe Rosinski, a retired Ford motor company engineer, […]

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Tags: #micro-fragmented adipose tissue, #Orthobiologics, #Regenerating Medicine Consult Service, Dr. Shane Shapiro, Mayo Clinic Center for Regenerative Medicine, Regenerative Medicine Therapeutic Suites


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