Research

October 7, 2021 · Leave a Comment

A regenerative reset for aging

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine could slow the clock on degenerative diseases that often ravage the golden years, a Mayo Clinic study finds. Life span has nearly doubled since the 1950s, but health span — the number of disease-free years — has not kept pace. According to a paper published in NPJ Regenerative Medicine., people are generally living […]

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Tags: #Aging, #Armin Garmany, #Center for Regenerative Medicine, #Dr. Andre Terzic, #Dr. Satsuki Yamada, #healthspan, #senescent cells


September 30, 2021 · Leave a Comment

Platelet-rich plasma: A regenerative approach to healing chronic wounds

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

By Madelyn Fell Platelet-rich plasma is the fraction of blood plasma that contains concentrations of platelets that are higher than baseline. Platelet-rich plasma attracts significant interest in the medical and research community since platelets possess various growth factors and cell parts that are critical for tissue repair and regeneration. Autologous platelet-rich plasma therapy uses injections of a […]

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Tags: #diabetic ulcers, #diabetic wounds, #Dr. Wenchun Qu, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Proceedings, #platelet rich plasma


September 23, 2021 · Leave a Comment

Dispelling the hype of stem cell interventions

By Susan Buckles Susan Buckles (@susanbuckles)

Physicians need more resources, tools and education to counsel patients about emerging stem cell therapies, a study in Mayo Clinic Proceedings concludes. Interest in regenerative procedures is mushrooming along with an increase in chronic diseases that have few therapeutic options. The study examined how physicians at the intersection of complex conditions, regenerative discoveries and responsible […]

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Tags: #Center for Regenerative Medicine, #Dr. Zubin Master, #Ethics, #Mayo Clinic Proceedings, #Regenerative Medicine Consult Service, #Stem cell therapy


September 16, 2021 · Leave a Comment

A robotic GPS for targeting, delivering regenerative biotherapies

By Susan Buckles Susan Buckles (@susanbuckles)

A remote-controlled bronchoscope that acts like a GPS system hunts down hard to find lung masses and accurately biopsies them, according to a Mayo Clinic collaborative study. This multisite research, which is published in Annals of Thoracic Surgery, lays the foundation for precisely finding early stage cancer and targeting it with regenerative biotherapeutics needed to […]

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Tags: #Biomanufacturing, #biotherapeutics, #bronchoscope, #Dr. Janani Reisenauer, #lung cancer, #Mayo Clinic Center for Regenerative Medicine, Dr. Julie Allickson


September 9, 2021 · Leave a Comment

A regenerative refresh to cosmetic procedures

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has launched a regenerative cosmetic service for patients aimed at resetting the body’s clock to a time of more youthful function and appearance. The Multidisciplinary Cosmetic Center at Mayo Clinic in Arizona pairs general and facial plastic surgery with dermatologists, gynecologists, vascular surgery, urologists and aestheticists to deliver services grounded in scientific evidence […]

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Tags: #Dr. Brittany Howard, #Dr. Michael Hinni, #fat grafting, #laser therapy, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Multidisciplinary Cosmetic Center, #platelet rich plasma, #rhinoplasty


September 2, 2021 · Leave a Comment

A fountain of youth for aging muscles

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine could hold the keys to rejuvenating older muscles, and research supporting that will be featured at the Mayo Clinic Symposium on Regenerative Medicine and Surgery. Preclinical research by Helen Blau, Ph.D., Stanford University School of Medicine, discovered a protein that triggers muscle loss and a way to block it to restore youthful muscle […]

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Tags: #Dr. Richard Hayden, #Helen Blau, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Symposium on Regenerative Medicine and Surgery, #muscle loss, #sarcopenia


August 19, 2021 · Leave a Comment

A new understanding of the inner workings of CAR-T cell therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: #Biomanufacturing, #CAR-T cell therapy, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative iimmunotherapies


August 12, 2021 · Leave a Comment

Regenerating the rotator cuff

By Susan Buckles Susan Buckles (@susanbuckles)

Preclinical studies discovered a cell-free bioactive material developed at Mayo Clinic triggered healing of one of the most common shoulder injuries. This Mayo Clinic research, published in Biomaterials, documented that purified exosome product —  also known as PEP — promoted repair of rotator cuff injuries faster and more effectively than surgery alone. The rotator cuff […]

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Tags: #Bioetherapeutics, #Dr Chunfeng Zhao, #Extracelluar vesicles, #Mayo Clinic Center for Regenerative Medicine, #Purified exosome products, #Regenerative biotherapeutics, #Rotator cuff injuries


August 5, 2021 · Leave a Comment

The importance of individualized regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

Individualized screening, guided by artificial intelligence (AI) and biomarkers, can optimize the transformative potential of regenerative medicine, according to a Mayo Clinic study. The paper, published in Biomarkers in Medicine, maintains that using new scientific tools to match the right biotherapeutics to the right patient ushers in the era of achieving tailored regenerative care. Conversely, […]

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Tags: #artificial intelliegence, #Cardiac regeneration, #cardiopoietic cells, #Dr. Andre Terzic, #Dr. Satsuki Yamada, #genetic testing, #Mayo Clinic Center for Regenerative Medicine


June 24, 2021 · Leave a Comment

Demystifying healing potential of stem cells

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic research has discovered proteins secreted by human stem cells that act as a “magic potion” to drive healing after a heart attack. The research uncovered that these cell-released regenerative particles harbor a pattern of functions mirrored in repair of the diseased heart, linking stem cell-transmitted information to the beneficial response of the recipient […]

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Tags: #Cardiac regeneration, #cardiopoietic cells, #Dr. Andre Terzic, #Dr. Kent Arrell, #Heart attack, #myocardial infarction


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