Research
August 15, 2022
Mayo Clinic announces a strategic collaboration for a new era of biomanufacturing
Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions. The collaboration brings together science, engineering and manufacturing to advance Mayo Clinic’s vision of bringing new cures to clinical care. The focus will be on therapies derived from human sources known as biologics — cells, blood, enzymes, […]
Tags: #biologics, #cell therapy, #Dr. Julie Allickson, #gene therapy, #Mayo Clinic Center for Regenerative Medicine, #National Resilience Inc.
August 2, 2022
Options for laryngeal regeneration
Mayo Clinic is using 3D printing as a new option to heal the larynx after cancer or traumatic injury. David Lott, M.D., a Mayo Clinic otolaryngologist and head and neck surgeon, is an expert who can speak about a pioneering procedure using 3D bioimplants and tissue engineering to regenerate the larynx, more commonly known as […]
Tags: #Dr. David Lott, #laryngeal cancer, #laryngectomy, #larynx transplant, #Mayo Clinic Center for Regenerative Medicine, #Tissue engineering
July 18, 2022
A preclinical step toward treating chronic dry mouth
Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]
Tags: #Dr. Jeffrey Janus, #Dr. Nagarajan Kannan, #Dry mouth, #head and neck cancer, #Mayo Clinic Center for Regenerative Medicine, #xerostomia
June 27, 2022
Biomanufacturing 101: Understanding a new era of therapeutics
Advancing cellular discoveries from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or genetically engineered cells […]
Tags: #biologics, #biotherapeutics, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine, #stem cell research
June 20, 2022
Addressing diversity barriers to regenerative medicine
With the promise of regenerative medicine comes the risk of widening health care disparities. Sometimes the newest discoveries, such as regenerative interventions, are out of reach for people in diverse ethnic or socioeconomic groups — or they may not understand or trust new options for healing. Mayo Clinic is trying to overcome those barriers by […]
Tags: #diversity, #Dr. Zubin Master, #Dr.Jorge Mallea, #equity and inclusion, #Mayo Clinic Center for Regenerative Medicine, #regeneration for all
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: #Dr. Andre Terzic, #Dr. Satsuki Yamada, #Heart disease, #Mayo Clinic Center for Regenerative Medicine, Dr. Kent Arrell
May 18, 2022
Training the next generation in regenerative medicine
Mayo Clinic is welcoming a new class of five students into the Regenerative Sciences track within the doctoral program in Mayo Clinic’s Graduate School of Biomedical Sciences, one of the first programs of its kind. Training the next generation of physicians and scientists to research, develop and deliver new biotherapies is critical to advancing the […]
Tags: #Aubrey Berger, #Dr. Isobel Scarisbrick, #Jimmy Cai, #Kyle Knofdzvnski, #Mayo Clinic Center for Regenerative Medicine, #Rafaela Simones Torigo, #Regenerative Sciences Training Program, #regenerative; medicine education, #Tiana Salomon
May 5, 2022
What’s behind patient requests for stem cells?
In one of the first studies of its kind, Mayo Clinic analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The findings could help health care professionals cut through misleading claims and better counsel patients. This research by Jennifer Arthurs; Zubin Master, […]
Tags: #biomedical ethics, #Dr. Shane Shapiro, #Dr. Zubin Master, #Jennifer Arthurs, #Mayo Clinic Center for Regenerative Medicine, #Orthobiologics, #Regenerative Medicine Therapeutic Suites, #Stem cell therapy, #stem cells
April 7, 2022
Saranya Wyles: Regenerating damaged skin
When she was just 8 years old, Saranya Wyles, M.D., Ph.D., would recite the stages of wound healing in Latin terms — rubor, tumor, calor, dolor and functio laesa— to her father at the dinner table. Decades later, that ingrained knowledge would be a cornerstone of her regenerative medicine research, education and practice at Mayo […]
Tags: #alopecia, #cellular senescence, #dermatology, #Regenerative medicine education, #Saranya Wyles, #scarring, #skin aging, #Wound healing
March 24, 2022
Regenerating damaged vocal cords
Cells from amniotic membrane show potential of repairing vocal cord injuries that don’t respond to standard care, Mayo Clinic discovered in preclinical research. The placental membrane provides a rich source of epithelial cells that could regenerate damaged tissue. Research by David Lott, M.D., a laryngeal surgeon in Arizona, found epithelial cells extracted after childbirth triggered […]
Tags: #Dr. David Lott, #epithelial cells, #Mayo Clinic Center for Regenerative Medicine, #Vocal cord injury, #Vocal cord regeneration