Cancer

November 10, 2023

Unleashing viruses aimed at killing cancer

By Susan Buckles Susan Buckles (@susanbuckles)

During breaks from his doctoral research in London, Richard Vile, Ph.D., would visit a pediatric brain tumor clinic next to his lab for inspiration. Seeing children suffer changed the course of his career, igniting his passion for finding cancer treatments that would be easier for people to tolerate. “I became very, very motivated to try […]

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Tags: #Cancer, #CAR-T cell therapy, #Dr. Richard Vile, #Mayo Clinic Center for Regenerative Biotherapeutics, #oncolytic virus


September 19, 2023

Harnessing the immune system to fight ovarian cancer

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic research is biomanufacturing an experimental, cell-based ovarian cancer vaccine and combining it with immunotherapy to study a “one-two punch” approach to halting disease progression in ovarian cancer patients. This research begins with a blood draw from women with advanced ovarian cancer whose tumors have returned after standard surgery and chemotherapy. White blood cells […]

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Tags: #dendritic cells, #Dr. Keith Knutson, #Dr. Matthew Block, #Mayo Clinic Center for Regenerative Biotherapeutics, #ovarian cancer, #ovarian cancer vaccine


June 13, 2022

Addressing the challenges of chimeric antigen receptor-T cell therapy

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]

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Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy


September 9, 2021

A regenerative refresh to cosmetic procedures

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has launched a regenerative cosmetic service for patients aimed at resetting the body’s clock to a time of more youthful function and appearance. The Multidisciplinary Cosmetic Center at Mayo Clinic in Arizona pairs general and facial plastic surgery with dermatologists, gynecologists, vascular surgery, urologists and aestheticists to deliver services grounded in scientific evidence […]

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Tags: #Dr. Brittany Howard, #Dr. Michael Hinni, #fat grafting, #laser therapy, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Multidisciplinary Cosmetic Center, #platelet rich plasma, #rhinoplasty


August 19, 2021

A new understanding of the inner workings of CAR-T cell therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: #Biomanufacturing, #CAR-T cell therapy, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative iimmunotherapies


January 7, 2021

Regenerating the larynx: A second chance at speech

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is leveraging advances in regenerative medicine to restore function for people whose lives have been drastically changed by a laryngectomy — surgery to remove the voice box. People without a voice box can neither speak with their natural voices nor breathe through their noses. Simple pleasures like smelling a bouquet of flowers or […]

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Tags: #Dr. David Lott, #Dr. Richard Hayden, #laryngeal cancer, #laryngectomy, #Larynx transplantation, #Mayo Clinic Center for Regenerative Medicine, #medical research, #Regenerative medicine


December 17, 2020

Diverse ways regenerative medicine is advancing health care

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine has contributed to patient care in 2020 more than ever before, bolstered by synergies in research, practice and education. Mayo Clinic’s Center for Regenerative Medicine is at the forefront of a biotherapy revolution in which health care advances from treating disease to restoring health. “The centrality of the body to regenerate itself is […]

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Tags: #CAR-T cell therapy, #Dr. Andre Terzic, #Dr. Atta Behfar, #exosomes, #Mayo Clinic Center for Regenerative Medicine, #medical research, #stem cell research


December 3, 2020

A regenerative detour for lymphedema

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is refining its regenerative approach to treating lymphedema, a debilitating buildup of fluid after cancer treatment. Research by Antonio Forte, M.D., Ph.D., a Mayo Clinic plastic surgeon, seeks to better pinpoint who is most likely to benefit from surgery aimed at regenerating a faulty lymphatic system. Mayo Clinic’s Center for Regenerative Medicine supports […]

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Tags: Antonio Forte, Breast cancer, lymphedema, lymphovenous bypass surgery, Mayo Clinic Center for Individualized Medicine, Mayo Clinic Center for Regenerative Medicine


October 1, 2020

Mining the molecular origins of breast cancer for new cures

By Susan Buckles Susan Buckles (@susanbuckles)

October is Breast Cancer Awareness Month, a time to focus on new strategies for prevention and early detection. Mayo Clinic Center for Regenerative Medicine and Mayo Clinic Cancer Center support stem cell biology research to uncover the molecular origins of breast cancer in order to bring new cures to the practice. Answering what are the […]

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Tags: Breast cancer, Breast Cancer Awareness Month, Center for Regenerative Medicine, Mayo Clinic Cancer Center, Mayo Clinic Department of Laboratory Medicine and Pathology, Nagarajan Kannan


September 23, 2020

A regenerative approach to facial reconstruction after cancer

By Susan Buckles Susan Buckles (@susanbuckles)

Growing up in southern California, Sabrina Falcon was a self-described “sun baby” whose love of the outdoors reached the skies. Years later the flight attendant who is working on her pilot’s license was diagnosed with skin cancer on her nose — the basal cell type that typically grows slowly with low risk of metastasizing. After […]

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Tags: Basal cell cancer, Brittany Howard, facial reconstruction surgery, Mayo Clinic Center for Regenerative Medicine, Mohs surgery, Shari Ochoa


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