With the promise of potential lifesaving treatments like chimeric antigen receptor (CAR) T-Cell therapy comes complex challenges. For instance: how can we be sure the right cells are going to the right patient? How can we communicate problems with manufacturing that would affect a patient’s treatment schedule? To address those concerns, Mayo Clinic startup [...]

The liver has the greatest regenerative capacity of any organ in the body. However, when the liver is injured beyond its ability to regenerate itself, and a transplant is not readily available, there are few options for patients. Led by Scott Nyberg, M.D., Ph.D., researchers are refining their own version of a bioartificial liver, known as [...]

Hypoplastic left heart syndrome (HLHS) is a complex and rare heart defect present at birth in which the left side of a child's heart is severely underdeveloped. At Mayo Clinic, physicians and researchers in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome are looking for ways to delay or even prevent heart failure [...]

The excitement at the 2019 Regenerative Medicine Minnesota meeting was palpable. Health care providers, scientists, educators, students, lawmakers and life sciences entrepreneurs mobilized to celebrate the BHAG—big hairy audacious goals in transforming health care. The BHAG challenge: develop new solutions and innovations that establish Minnesota as a world class leader and destination for advancing regenerative medicine [...]

Stroke is the leading cause of permanent disability in the U.S., striking nearly 800,000 people each year, according to the Centers for Disease Control and Prevention. In the last decade, there has been preclinical research that led to a small number of early phase clinical trials using mesenchymal stem cells (MSCs) as [...]