Biomanufacturing

August 15, 2022

Mayo Clinic announces a strategic collaboration for a new era of biomanufacturing

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions. The collaboration brings together science, engineering and manufacturing to advance Mayo Clinic’s vision of bringing new cures to clinical care. The focus will be on therapies derived from human sources known as biologics — cells, blood, enzymes, […]

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Tags: #biologics, #cell therapy, #Dr. Julie Allickson, #gene therapy, #Mayo Clinic Center for Regenerative Medicine, #National Resilience Inc.


August 2, 2022

Options for laryngeal regeneration

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is using 3D printing as a new option to heal the larynx after cancer or traumatic injury. David Lott, M.D., a Mayo Clinic otolaryngologist and head and neck surgeon, is an expert who can speak about a pioneering procedure using 3D bioimplants and tissue engineering to regenerate the larynx, more commonly known as […]

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Tags: #Dr. David Lott, #laryngeal cancer, #laryngectomy, #larynx transplant, #Mayo Clinic Center for Regenerative Medicine, #Tissue engineering


July 11, 2022

Bringing regenerative technology of the future to patients today

By Susan Buckles Susan Buckles (@susanbuckles)

“The sky’s the limit,” “possibility” and “potential cure for disease” are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo’s panel discussion showcased how it is advancing regenerative medicine through industry collaborations that accelerate scientific discoveries to early stage clinical trials. […]

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Tags: #Dr. Abba Zubair, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Saranya Wyles, #Mayo Clinic Center for Regenerative Medicine, #World Stem Cell Summit


June 27, 2022

Biomanufacturing 101: Understanding a new era of therapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Advancing cellular discoveries from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or genetically engineered cells […]

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Tags: #biologics, #biotherapeutics, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine, #stem cell research


June 13, 2022

Addressing the challenges of chimeric antigen receptor-T cell therapy

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]

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Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy


April 15, 2022

Global spotlight on Mayo Clinic’s regenerative biotherapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic will showcase its work in discovering, manufacturing and delivering next-generation biotherapeutics with an international audience interested in advancing lifesaving cell and gene therapies. Mayo Clinic’s Center for Regenerative Medicine is sponsoring a roundtable discussion, “Mayo Clinic: Building the Ecosystem in Regenerative Biotherapeutics,” at the International Society for Cell & Gene Therapy’s ISCT 2022 […]

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Tags: #Dr. Claudia Lucchinetti, #Dr. Julie Allickson, #Dr. Stephen Ekker, #Dr. William Faubion, #International Society for Cell & Gene Therapy, #Manu Nair, #Mayo Clinic Center for Regenerative Medicine


February 3, 2022

The regenerative operating room of the future

By Susan Buckles Susan Buckles (@susanbuckles)

Envisioning the future of regenerative medicine elicits images of an operating room that also is a manufacturing facility. Patients undergoing surgery could have immediate access to products biomanufactured within the operating room or even within their own bodies. Products such as tissue engineered for targeted healing or 3D-printed scaffolds that repair diseased organs, bones or […]

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Tags: #3D printing, #Dr. Brittany Howard, #Dr. David Lo, #Dr. Juergen Neubauer, #Dr. Michael McPhail, #Mayo Clinic Center for Regenerative Medicine


January 20, 2022

Preparing to deliver next-generation therapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is among the academic medical centers on the cusp of biomanufacturing next-generation cell and gene therapies that offer hope of new cures for rare and complex diseases. Biomanufacturing this new era of biologic medicines is much different than manufacturing pharmaceuticals from complex molecules. It requires highly specialized lab infrastructure, new processes and new […]

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Tags: #CAR T-Therapy, #cell therapies, #Dr. Allen Dietz, #Dr. Michael Gustafson, #Mayo Clinic Center for Regenerative Medicine


January 6, 2022

Reimagining stem cell cultivation

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has discovered how to microencapsulate pluripotent stem cells to potentially make them easier and less expensive to process and more effective for fighting disease. This research by Alexander Revzin, Ph.D., a Mayo Clinic biomedical engineer, is published in Bioactive Materials. “Human pluripotent stem cells hold considerable promise as a source of adult cellsfor […]

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Tags: #Dr. Alexander Revzin, #induced pluripotent stem cells, #Mayo Clinic Center for Regenerative Medicine, #stem cell research


December 9, 2021

A year of new directions and advancements for regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

2021 has been a year of significant innovation across the field of regenerative medicine at Mayo Clinic. Important advancements in preclinical research, as well as new regenerative treatments for patients, further are solidifying Mayo Clinic’s reputation as a world-class leader in regenerative medicine. Regenerative medicine is still a relatively new field of practice, representing a […]

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Tags: #CAR T-cell therapy, #Dr. Janani Reisenauer, #Dr. Julie Allickson, #Dr. Saad Kenderian, #Mayo Clinic Symposium on Regenerative Medicine and Surgery, #Regenerative cosmetics, #Wound healing


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