Biomanufacturing
November 27, 2023
Mayo Clinic seeks to harness the power of cells, tissue and genes by delivering first-of-their kind therapeutics for patients in early-stage clinical trials. Mayo Clinic’s Center for Regenerative Biotherapeutics is leading an effort that is at the crossroads of biology, engineering, industry and medicine to expand biomanufacturing for rare and complex disorders. Biomanufacturing is the […]
Tags: #biologics, #Dr. Cynthia Wilkins, #Dr. Julie Allickson, #Dr. Snigdha Rai, #Immunotherapies, #Mayo Clinic Center for Regenerative Biotherapetics
November 10, 2023
Unleashing viruses aimed at killing cancer
During breaks from his doctoral research in London, Richard Vile, Ph.D., would visit a pediatric brain tumor clinic next to his lab for inspiration. Seeing children suffer changed the course of his career, igniting his passion for finding cancer treatments that would be easier for people to tolerate. “I became very, very motivated to try […]
Tags: #Cancer, #CAR-T cell therapy, #Dr. Richard Vile, #Mayo Clinic Center for Regenerative Biotherapeutics, #oncolytic virus
September 19, 2023
Harnessing the immune system to fight ovarian cancer
Mayo Clinic research is biomanufacturing an experimental, cell-based ovarian cancer vaccine and combining it with immunotherapy to study a “one-two punch” approach to halting disease progression in ovarian cancer patients. This research begins with a blood draw from women with advanced ovarian cancer whose tumors have returned after standard surgery and chemotherapy. White blood cells […]
Tags: #dendritic cells, #Dr. Keith Knutson, #Dr. Matthew Block, #Mayo Clinic Center for Regenerative Biotherapeutics, #ovarian cancer, #ovarian cancer vaccine
September 1, 2023
A passion for bringing new biotherapeutics to patients
A yearning to heal patients and excitement for the new and growing field of biotherapeutics are what attracted Wen Lu, M.D., to her new role as medical director of Mayo Clinic’s Center for Regenerative Biotherapeutics in Rochester. Dr. Lu will provide clinical input on which biotherapeutics hold the most promise and should advance to early […]
Tags: #biologics, #CAR T-cell therapy, #cell therapy, #Dr. Wen Lu, #Mayo Clinic Center for Regenerative Medicine
July 31, 2023
Driven by family, fueled by hope: Mayo Clinic researcher fights against Type 1 diabetes
Quinn Peterson, Ph.D., was a graduate student working on a team to develop new chemotherapy drugs when a life-changing phone call reset the course of his career. His daughter, Clarissa, had been diagnosed with Type 1 diabetes. Neither he nor his wife had any known family history of the disease. “Given my background as a […]
Tags: #biomedical research, #diabetes research, #Dr. Quinn Peterson, #Islet research, #Mayo Clinic Center for Regenerative Biotherapeutics, #medical research, #Type 1 diabetes
August 15, 2022
Mayo Clinic announces a strategic collaboration for a new era of biomanufacturing
Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions. The collaboration brings together science, engineering and manufacturing to advance Mayo Clinic’s vision of bringing new cures to clinical care. The focus will be on therapies derived from human sources known as biologics — cells, blood, enzymes, […]
Tags: #biologics, #cell therapy, #Dr. Julie Allickson, #gene therapy, #Mayo Clinic Center for Regenerative Medicine, #National Resilience Inc.
August 2, 2022
Options for laryngeal regeneration
Mayo Clinic is using 3D printing as a new option to heal the larynx after cancer or traumatic injury. David Lott, M.D., a Mayo Clinic otolaryngologist and head and neck surgeon, is an expert who can speak about a pioneering procedure using 3D bioimplants and tissue engineering to regenerate the larynx, more commonly known as […]
Tags: #Dr. David Lott, #laryngeal cancer, #laryngectomy, #larynx transplant, #Mayo Clinic Center for Regenerative Medicine, #Tissue engineering
July 11, 2022
Bringing regenerative technology of the future to patients today
“The sky’s the limit,” “possibility” and “potential cure for disease” are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo’s panel discussion showcased how it is advancing regenerative medicine through industry collaborations that accelerate scientific discoveries to early stage clinical trials. […]
Tags: #Dr. Abba Zubair, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Saranya Wyles, #Mayo Clinic Center for Regenerative Medicine, #World Stem Cell Summit
June 27, 2022
Biomanufacturing 101: Understanding a new era of therapeutics
Advancing cellular discoveries from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or genetically engineered cells […]
Tags: #biologics, #biotherapeutics, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine, #stem cell research
June 13, 2022
Addressing the challenges of chimeric antigen receptor-T cell therapy
Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]
Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy