May 3, 2023
Regenerative medicine paves the way for a heart transplant
Travis Kelchen’s path to a regenerative intervention at Mayo Clinic began when he was on vacation in the Dominican Republic and could barely walk at his brother’s wedding. At 31, he was tired, winded and losing color. Within months, his cardiologist said he could not do anything more for Travis’ congenital heart defect and referred […]
Tags: #Dr. Atta Behfar, #Ebstein anomaly, #Heart transplant, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Proceedings, #Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program, #Travis Kelchen
August 30, 2022
A new name for Center for Regenerative Medicine
Mayo Clinic’s Center for Regenerative Medicine has been renamed the Center for Regenerative Biotherapeutics. The name change reflects Mayo’s new strategic focus: manufacturing next-generation biotherapeutics for patients. The new name emphasizes how regenerative medicine at Mayo Clinic has evolved to advance groundbreaking discoveries toward curative products — biotherapeutics — for patients. The Center for Regenerative […]
Tags: #Biomanufacturing, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine
August 15, 2022
Mayo Clinic announces a strategic collaboration for a new era of biomanufacturing
Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions. The collaboration brings together science, engineering and manufacturing to advance Mayo Clinic’s vision of bringing new cures to clinical care. The focus will be on therapies derived from human sources known as biologics — cells, blood, enzymes, […]
Tags: #biologics, #cell therapy, #Dr. Julie Allickson, #gene therapy, #Mayo Clinic Center for Regenerative Medicine, #National Resilience Inc.
August 2, 2022
Options for laryngeal regeneration
Mayo Clinic is using 3D printing as a new option to heal the larynx after cancer or traumatic injury. David Lott, M.D., a Mayo Clinic otolaryngologist and head and neck surgeon, is an expert who can speak about a pioneering procedure using 3D bioimplants and tissue engineering to regenerate the larynx, more commonly known as […]
Tags: #Dr. David Lott, #laryngeal cancer, #laryngectomy, #larynx transplant, #Mayo Clinic Center for Regenerative Medicine, #Tissue engineering
July 18, 2022
A preclinical step toward treating chronic dry mouth
Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]
Tags: #Dr. Jeffrey Janus, #Dr. Nagarajan Kannan, #Dry mouth, #head and neck cancer, #Mayo Clinic Center for Regenerative Medicine, #xerostomia
July 11, 2022
Bringing regenerative technology of the future to patients today
“The sky’s the limit,” “possibility” and “potential cure for disease” are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo’s panel discussion showcased how it is advancing regenerative medicine through industry collaborations that accelerate scientific discoveries to early stage clinical trials. […]
Tags: #Dr. Abba Zubair, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Saranya Wyles, #Mayo Clinic Center for Regenerative Medicine, #World Stem Cell Summit
June 27, 2022
Biomanufacturing 101: Understanding a new era of therapeutics
Advancing cellular discoveries from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or genetically engineered cells […]
Tags: #biologics, #biotherapeutics, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine, #stem cell research
June 20, 2022
Addressing diversity barriers to regenerative medicine
With the promise of regenerative medicine comes the risk of widening health care disparities. Sometimes the newest discoveries, such as regenerative interventions, are out of reach for people in diverse ethnic or socioeconomic groups — or they may not understand or trust new options for healing. Mayo Clinic is trying to overcome those barriers by […]
Tags: #diversity, #Dr. Zubin Master, #Dr.Jorge Mallea, #equity and inclusion, #Mayo Clinic Center for Regenerative Medicine, #regeneration for all
June 13, 2022
Addressing the challenges of chimeric antigen receptor-T cell therapy
Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]
Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: #Dr. Andre Terzic, #Dr. Satsuki Yamada, #Heart disease, #Mayo Clinic Center for Regenerative Medicine, Dr. Kent Arrell