June 27, 2022
Biomanufacturing 101: Understanding a new era of therapeutics
Advancing cellular discoveries from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or genetically engineered cells […]
Tags: #biologics, #biotherapeutics, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Medicine, #stem cell research
June 20, 2022
Addressing diversity barriers to regenerative medicine
With the promise of regenerative medicine comes the risk of widening health care disparities. Sometimes the newest discoveries, such as regenerative interventions, are out of reach for people in diverse ethnic or socioeconomic groups — or they may not understand or trust new options for healing. Mayo Clinic is trying to overcome those barriers by […]
Tags: #diversity, #Dr. Zubin Master, #Dr.Jorge Mallea, #equity and inclusion, #Mayo Clinic Center for Regenerative Medicine, #regeneration for all
June 13, 2022
Addressing the challenges of chimeric antigen receptor-T cell therapy
Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]
Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: #Dr. Andre Terzic, #Dr. Satsuki Yamada, #Heart disease, #Mayo Clinic Center for Regenerative Medicine, Dr. Kent Arrell
May 18, 2022
Training the next generation in regenerative medicine
Mayo Clinic is welcoming a new class of five students into the Regenerative Sciences track within the doctoral program in Mayo Clinic’s Graduate School of Biomedical Sciences, one of the first programs of its kind. Training the next generation of physicians and scientists to research, develop and deliver new biotherapies is critical to advancing the […]
Tags: #Aubrey Berger, #Dr. Isobel Scarisbrick, #Jimmy Cai, #Kyle Knofdzvnski, #Mayo Clinic Center for Regenerative Medicine, #Rafaela Simones Torigo, #Regenerative Sciences Training Program, #regenerative; medicine education, #Tiana Salomon
May 5, 2022
What’s behind patient requests for stem cells?
In one of the first studies of its kind, Mayo Clinic analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The findings could help health care professionals cut through misleading claims and better counsel patients. This research by Jennifer Arthurs; Zubin Master, […]
Tags: #biomedical ethics, #Dr. Shane Shapiro, #Dr. Zubin Master, #Jennifer Arthurs, #Mayo Clinic Center for Regenerative Medicine, #Orthobiologics, #Regenerative Medicine Therapeutic Suites, #Stem cell therapy, #stem cells
April 28, 2022
Students embrace teaching to advance regenerative medicine
A group of Mayo Clinic students is going beyond their rigorous research schedules to help up-and-comers and established health care professionals alike learn about the emerging practice of regenerative medicine. As teaching assistants for Mayo Clinic’s Regenerative Medicine and Surgery “selectives,” they are channeling their enthusiasm for this new area of practice into weeklong courses […]
Tags: #Armin Garmany, #Connor Lentz, #Dr. Saranya Wyles, #Eric Grewal, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Regenerative Medicine and Surgery Course, #Regenerative medicine education
April 15, 2022
Global spotlight on Mayo Clinic’s regenerative biotherapeutics
Mayo Clinic will showcase its work in discovering, manufacturing and delivering next-generation biotherapeutics with an international audience interested in advancing lifesaving cell and gene therapies. Mayo Clinic’s Center for Regenerative Medicine is sponsoring a roundtable discussion, “Mayo Clinic: Building the Ecosystem in Regenerative Biotherapeutics,” at the International Society for Cell & Gene Therapy’s ISCT 2022 […]
Tags: #Dr. Claudia Lucchinetti, #Dr. Julie Allickson, #Dr. Stephen Ekker, #Dr. William Faubion, #International Society for Cell & Gene Therapy, #Manu Nair, #Mayo Clinic Center for Regenerative Medicine
March 24, 2022
Regenerating damaged vocal cords
Cells from amniotic membrane show potential of repairing vocal cord injuries that don’t respond to standard care, Mayo Clinic discovered in preclinical research. The placental membrane provides a rich source of epithelial cells that could regenerate damaged tissue. Research by David Lott, M.D., a laryngeal surgeon in Arizona, found epithelial cells extracted after childbirth triggered […]
Tags: #Dr. David Lott, #epithelial cells, #Mayo Clinic Center for Regenerative Medicine, #Vocal cord injury, #Vocal cord regeneration
March 3, 2022
The immune system and bone regeneration
Growing up as a student athlete in Cincinnati, Joe Panos had more than his fair share of visits to the orthopedist for sports injuries. The care he received for conditions ranging from pitcher’s elbow to soccer sprains so impressed him that he vowed one day to be the physician instead of the patient. Now Panos, […]
Tags: #BMP-2 growth factor, #bone regeneration, #Dr. Christopher Evans, #Mayo Clinic Alix School of Medicine, #Mayo Clinic Center for Regenerative Medicine, #ON Foundation, #Orthoregeneration Award