Items Tagged ‘#Mayo Clinic Center for Regenerative Biotherapeutics’

January 17, 2024

Developing relationships to advance biotherapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic’s pioneering approach to biotherapeutics is in the spotlight at a national biotech conference aimed at bringing new life-saving cell and gene therapies to patients. Leaders from Mayo’s Center for Regenerative Biotherapeutics will speak to attendees at the Advanced Therapies Week conference about the role of teamwork and Mayo Clinic’s three-shield approach of research, […]

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Tags: #Advanced Therapies Week, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Saad Kenderian, #Dr. Timothy Nelson, #Mayo Clinic Center for Regenerative Biotherapeutics


December 19, 2023

A year of advancing novel regenerative biotherapeutics toward patient care

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic’s Center for Regenerative Biotherapeutics has advanced the development and biomanufacturing of novel therapeutics, called biologics, for cancer and inflammatory conditions into clinical trials. “My dream has been to develop innovative technologies that go beyond treating symptoms to curing diseases. The ultimate aim is to ensure that these advancements are accessible to all patients […]

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Tags: #biomedical research, #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Julie Allickson, #Dr. Keith Knutson, #Dr. Matthew Block, #Dr. Richard Vile, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Biotherapeutics, #ovarian cancer


November 30, 2023

Rebuilding bigger, stronger hearts

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

Reprint from Mayo Clinic Alumni magazine, 2023, issue 3 Timothy Nelson, M.D., Ph.D., intended to be a cardiothoracic surgeon. “As a student in the Medical Scientist Training Program at the Medical College of Wisconsin, I observed a lot of cases and remember the joys of giving families hope that we could repair defects,” he says. “I […]

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Tags: #cardiomyocytes, #Dr. Timothy Nelson, #Hypoplastic Left Heart Syndrome, #Mayo Clinic Center for Regenerative Biotherapeutics


November 10, 2023

Unleashing viruses aimed at killing cancer

By Susan Buckles Susan Buckles (@susanbuckles)

During breaks from his doctoral research in London, Richard Vile, Ph.D., would visit a pediatric brain tumor clinic next to his lab for inspiration. Seeing children suffer changed the course of his career, igniting his passion for finding cancer treatments that would be easier for people to tolerate. “I became very, very motivated to try […]

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Tags: #Cancer, #CAR-T cell therapy, #Dr. Richard Vile, #Mayo Clinic Center for Regenerative Biotherapeutics, #oncolytic virus


October 31, 2023

Paradigm shift in fistula care

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

From Mayo Clinic Alumni Magazine, 2023 issue 3 It started with a chance encounter in the Gonda Building on Mayo Clinic’s Rochester campus in 2013. Colorectal surgeon Eric Dozois, M.D., chair, Division of Colon and Rectal Surgery, ran into gastroenterologist William Faubion Jr., M.D., Division of Gastroenterology and Hepatology, and shared an idea. A fellow in colorectal […]

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Tags: #biomedical research, #Dr. Allan Dietz, #Dr. Eric Dozois, #Dr. William Faubion Jr., #Mayo Clinic Center for Regenerative Biotherapeutics, #Perianal fistula, #Stem cell therapy


October 27, 2023

Engineering stem cells to treat liver disease

By Susan Buckles Susan Buckles (@susanbuckles)

During clinical rotations in medical school, Kianna Nguyen encountered many patients with liver failure and was struck by a grim reality: Their only hope was a transplant. The shortage of donor organs and therapeutic options was at once frustrating and inspirational, triggering her research interest in cellular therapies for liver failure. “Research provides us with […]

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Tags: #Dr. Alexander Revzin, #embryonic stem cells, #Kianna Nguyen, #Liver failure, #Mayo Clinic Alix School of Mediciine, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Graduate School of Biomedical Sciences, #Stem cell encapsulation, #stem cells


October 11, 2023

Mayo Clinic prepares to biomanufacture a new CAR-T cell therapy for B-cell blood cancers        

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic research has developed a new type of chimeric antigen receptor-T cell therapy (CAR-T cell therapy) aimed at killing B-cell blood cancers that have returned and are no longer responding to treatment. This pioneering technology, designed and developed in the lab of Hong Qin, M.D., Ph.D., killed B-cell tumors grown in the laboratory and […]

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Tags: #B-cell blood cancers, #Biomanufacturing, #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Biotherapeutics


September 19, 2023

Harnessing the immune system to fight ovarian cancer

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic research is biomanufacturing an experimental, cell-based ovarian cancer vaccine and combining it with immunotherapy to study a “one-two punch” approach to halting disease progression in ovarian cancer patients. This research begins with a blood draw from women with advanced ovarian cancer whose tumors have returned after standard surgery and chemotherapy. White blood cells […]

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Tags: #dendritic cells, #Dr. Keith Knutson, #Dr. Matthew Block, #Mayo Clinic Center for Regenerative Biotherapeutics, #ovarian cancer, #ovarian cancer vaccine


August 18, 2023

Advancing understanding of CAR-T cell therapy for cancer

By MayoRegMed MayoRegMed (@mayoregmed)

By Kate Ledger This article on a Mayo Clinic Regenerative Sciences Training Program student is taken from a series of articles that feature the work of graduate students as they near the end of their Ph.D. training at Mayo Clinic Graduate School of Biomedical Sciences. Students talk about their research journeys, lessons they learned along the […]

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Tags: #biomedical research, #CAR T-cell therapy, #Claudia Manriquez Roman, #Mayo Clinic Center for Regenerative Biotherapeutics, #Regenerative Sciences Training Program


August 10, 2023

Regenerative Medicine Minnesota awards 3 grants to Mayo Clinic researchers

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative Medicine Minnesota, a statewide bipartisan initiative, has awarded three grants to Mayo Clinic for research to improve cancer treatment and nerve regeneration. Recognizing the need for a new approach to healthcare, Minnesota lawmakers established Regenerative Medicine Minnesota a decade ago. This state funded initiative is focused on advancing regenerative medicine in research, technology, education […]

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Tags: #CAR-T cell therapy, #Dr. Alexander Shin, #Dr. Ismail Can, #Dr. Kevin Loutherback, #Mayo Clinic Center for Regenerative Biotherapeutics, #nerve regeneration


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