July 13, 2023
CAR-T cell therapy restores hope for leukemia patient
Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says […]
Tags: #biomedical research, #CAR T-cell therapy, #chronic lymphocytic leukemia, #Clinical trials, #Dr. Saad Kenderian, #Mayo Clinic Center Regenerative Biotherapeutics, #medical research
June 13, 2022
Addressing the challenges of chimeric antigen receptor-T cell therapy
Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]
Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy
December 9, 2021
A year of new directions and advancements for regenerative medicine
2021 has been a year of significant innovation across the field of regenerative medicine at Mayo Clinic. Important advancements in preclinical research, as well as new regenerative treatments for patients, further are solidifying Mayo Clinic’s reputation as a world-class leader in regenerative medicine. Regenerative medicine is still a relatively new field of practice, representing a […]
Tags: #CAR T-cell therapy, #Dr. Janani Reisenauer, #Dr. Julie Allickson, #Dr. Saad Kenderian, #Mayo Clinic Symposium on Regenerative Medicine and Surgery, #Regenerative cosmetics, #Wound healing
August 19, 2021
A new understanding of the inner workings of CAR-T cell therapy
Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]
Tags: #Biomanufacturing, #CAR-T cell therapy, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative iimmunotherapies
April 23, 2020
Training the workforce of the future in CAR T-cell therapy
Mayo Clinic is equipping the next generation of physician-scientists with knowledge to bring chimeric antigenic receptor (CAR) T-cell therapy to more patients. One of the first medical centers to offer CAR T, Mayo Clinic is sharing its unique knowledge of this regenerative immunotherapy in a first-of-its kind graduate mini course offered through the Mayo Clinic […]
Tags: #Biomanufacturing, #CAR T-cell therapy, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine
September 5, 2019
Meet researcher Saad Kenderian: Using regenerative cell therapy to recognize and attack cancer
For as long as he can remember, Saad Kenderian, M.B., Ch.B., wanted to be a physician. Nothing could blunt his resolve –not even when exploding bombs and trappings of war forced the medical school in his hometown of Baghdad, Iraq, to close briefly. It is with that same determination he conducts Mayo Clinic research into […]
Tags: #CAR T-cell therapy, #Dr. Saad Kenderian, #Immunotherapy, #Leukemia, #Lymphoma, #Mayo Clinic Cancer Center, #Regenerative therapies, Mayo Clinic Center for Regenerative Medicine