September 1, 2023
A passion for bringing new biotherapeutics to patients
A yearning to heal patients and excitement for the new and growing field of biotherapeutics are what attracted Wen Lu, M.D., to her new role as medical director of Mayo Clinic’s Center for Regenerative Biotherapeutics in Rochester. Dr. Lu will provide clinical input on which biotherapeutics hold the most promise and should advance to early […]
Tags: #biologics, #CAR T-cell therapy, #cell therapy, #Dr. Wen Lu, #Mayo Clinic Center for Regenerative Medicine
August 18, 2023
Advancing understanding of CAR-T cell therapy for cancer
By MayoRegMed
By Kate Ledger This article on a Mayo Clinic Regenerative Sciences Training Program student is taken from a series of articles that feature the work of graduate students as they near the end of their Ph.D. training at Mayo Clinic Graduate School of Biomedical Sciences. Students talk about their research journeys, lessons they learned along the […]
Tags: #biomedical research, #CAR T-cell therapy, #Claudia Manriquez Roman, #Mayo Clinic Center for Regenerative Biotherapeutics, #Regenerative Sciences Training Program
July 13, 2023
CAR-T cell therapy restores hope for leukemia patient
Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says […]
Tags: #biomedical research, #CAR T-cell therapy, #chronic lymphocytic leukemia, #Clinical trials, #Dr. Saad Kenderian, #Mayo Clinic Center Regenerative Biotherapeutics, #medical research
February 16, 2023
Recognizing the potential of gene-modified T cells to transform medicine, researchers at the University of Pennsylvania have continued to innovate with clinical trials over the past two decades. In a convergence of science, medicine and entrepreneurship, an industry collaborator brought the first breakthrough gene therapy for cancer to market in the U.S. in 2017 — […]
Tags: #biologics, #CAR T-cell therapy, #Dr. Bruce Levine, #Dr. Richard Hayden, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine and Surgery
January 5, 2023
Expanding regenerative biotherapeutics to new practice areas
As a physician at the forefront of new cancer therapies, Yi Lin, M.D., Ph.D., understands the highs and lows that patients experience. Will the latest technologies slow or stop disease? If not, is this the last, best option? Dr. Lin, a hematologist, sees the need for a new class of drugs that provides different treatment […]
Tags: #cancer immunotherapies, #CAR T-cell therapy, #Dr. Yi Lin, #gene therapy, #Mayo Clinic Center for Regenerative Biotherapeutics, #tissue engineeering
June 13, 2022
Addressing the challenges of chimeric antigen receptor-T cell therapy
Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]
Tags: #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine, #regenerative immunotherapy
December 9, 2021
A year of new directions and advancements for regenerative medicine
2021 has been a year of significant innovation across the field of regenerative medicine at Mayo Clinic. Important advancements in preclinical research, as well as new regenerative treatments for patients, further are solidifying Mayo Clinic’s reputation as a world-class leader in regenerative medicine. Regenerative medicine is still a relatively new field of practice, representing a […]
Tags: #CAR T-cell therapy, #Dr. Janani Reisenauer, #Dr. Julie Allickson, #Dr. Saad Kenderian, #Mayo Clinic Symposium on Regenerative Medicine and Surgery, #Regenerative cosmetics, #Wound healing
April 23, 2020
Training the workforce of the future in CAR T-cell therapy
Mayo Clinic is equipping the next generation of physician-scientists with knowledge to bring chimeric antigenic receptor (CAR) T-cell therapy to more patients. One of the first medical centers to offer CAR T, Mayo Clinic is sharing its unique knowledge of this regenerative immunotherapy in a first-of-its kind graduate mini course offered through the Mayo Clinic […]
Tags: #Biomanufacturing, #CAR T-cell therapy, #Dr. Saad Kenderian, #Mayo Clinic Center for Regenerative Medicine
September 5, 2019
Meet researcher Saad Kenderian: Using regenerative cell therapy to recognize and attack cancer
For as long as he can remember, Saad Kenderian, M.B., Ch.B., wanted to be a physician. Nothing could blunt his resolve –not even when exploding bombs and trappings of war forced the medical school in his hometown of Baghdad, Iraq, to close briefly. It is with that same determination he conducts Mayo Clinic research into […]
Tags: #CAR T-cell therapy, #Dr. Saad Kenderian, #Immunotherapy, #Leukemia, #Lymphoma, #Mayo Clinic Cancer Center, #Regenerative therapies, Mayo Clinic Center for Regenerative Medicine
August 6, 2019
Mayo Clinic Startup Earns World Economic Forum Award
With the promise of potential lifesaving treatments like chimeric antigen receptor (CAR) T-Cell therapy comes complex challenges. For instance: how can we be sure the right cells are going to the right patient? How can we communicate problems with manufacturing that would affect a patient’s treatment schedule? To address those concerns, Mayo Clinic startup company […]
Tags: #Andrew Danielsen, #CAR T-cell therapy, #Dr. Jeffrey Winters, #Mayo Clinic Department of Laboratory Medicine and Pathology, #Mayo Clinic Ventures, #The World Economic Forum, #Vineti, Dr. Allan Dietz, Dr. Yi Lin, Mayo Clinic Center for Regenerative Medicine