November 3, 2020
3D brain models advance Alzheimer’s disease research at Mayo Clinic
A 3D model of brain organoids — “a minibrain in a dish” — mimics human brain structure and provides a new scientific strategy for exploring the pathology of Alzheimer’s disease, Mayo Clinic research discovered. The study, which was published in Nature Communications, finds that the minibrain — an induced pluripotent stem cell-derived cerebral organoid 3D […]
Tags: Alzheimer's disease, brain organoids, Guojun Bu, Mayo Clinic Center for Regenerative Medicine, pluripotent stem cells
September 10, 2020
Could regenerative medicine hold a key to understanding Alzheimer’s disease?
September is World Alzheimer’s Month, a time to raise awareness of research to unlock scientific mysteries around a disease that robs people of their memory, independence and ultimately their ability to think and reason. Focused on disease causes and cures, the Center for Regenerative Medicine is driving innovation as a collaborative partner in Mayo Clinic’s […]
Tags: Alzheimer's disease, Center for Regenerative Medicine, dementia, Guojun Bu, Melissa Murray, Neurodegenerative Diseases, Regenerative Medicine Biotrust
August 23, 2018
Understanding the Connection Often people with diabetes have brain changes that are hallmarks of both Alzheimer’s disease and vascular dementia. Some researchers believe that each condition fuels the damage caused by the other. That link may occur as a result of the ways that type 2 diabetes affects the ability of the brain and other […]
Tags: Alzheimer's disease, Center for Regenerative Medicine, diabetes, islet regeneration, neurobiology, stem cells, type 3 diabetes
October 5, 2017
Alzheimer’s Researcher Receives MERIT Award
This story first appeared on Mayo Clinic’s medical science blog, Advancing the Science. Dr. Bu is the associate director for the Center for Regenerative Medicine in Florida. Neuroscientist Guojun Bu, Ph.D., Mary Lowell Leary Professor of Medicine, on Mayo Clinic’s campus in Florida, has been selected to receive the prestigious Method to Extend Research in Time (MERIT) Award. […]
Tags: Alzheimer's disease, amyloid, APOE, awards, Dr. Guojun Bu, Dr. Tushar Patel, Florida, Florida research, National Advisory Council on Aging, National Institute on Aging, NIA, NIH