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May 31, 2023

Mayo Clinic regenerative biotherapeutics showcased at international conference

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic physicians and scientists are sharing their expertise in regenerative biotherapeutics at a global conference in Paris this week. The International Society for Cell and Gene Therapy (ISCT) conference, Celebrating Progress, Building the Future, is bringing together roughly 2,000 people from around the world that work in industry, academia, government and health care. Together […]

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Tags: #Dr. Abba Zubair, #Dr. Allan Dietz, #Dr. Burcin Taner, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Prathibha Varkey, #Dr. Richard Hayden, #Dr. Timothy Nelson, #Dr. Wenchun Qu, #Dr. Yi Lin, #International Society for Cell and Gene Therapy


May 18, 2023

Like filling a pothole: Cell therapy for cartilage repair

By Susan Buckles Susan Buckles (@susanbuckles)

Growing up in the Netherlands, Daniel Saris, M.D., Ph.D., was exposed to the wonders of science at a young age. He listened to his father, a physicist, when he spoke at scientific conferences. His mother, an English teacher, encouraged learning about diverse societies. These experiences would grow into Dr. Saris’ career as an orthopedic surgeon […]

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Tags: #cartilage injury, #cartilage repair, #Dr. Daniel Saris, #joint replacement, #knee injury, #Mayo Clinic Center for Regenerative Biotherapeutics, #orthopedics


May 3, 2023

Regenerative medicine paves the way for a heart transplant

By Susan Buckles Susan Buckles (@susanbuckles)

Travis Kelchen’s path to a regenerative intervention at Mayo Clinic began when he was on vacation in the Dominican Republic and could barely walk at his brother’s wedding. At 31, he was tired, winded and losing color. Within months, his cardiologist said he could not do anything more for Travis’ congenital heart defect and referred […]

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Tags: #Dr. Atta Behfar, #Ebstein anomaly, #Heart transplant, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Proceedings, #Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program, #Travis Kelchen


April 25, 2023

Orthobiologics can be nature’s healing agents

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic physician-scientists are working on regenerative biotherapeutics such as orthobiologics and other regenerative bioinjectables to bring advanced procedures to more patients. Orthobiologics are biological agents that stimulate healing when standard therapies don’t work. Examples are platelet-rich plasma — platelets spun from a patient’s blood that promote cell repair— and bone marrow aspirate concentrate that […]

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Tags: #bone marrow aspirate concentrate, #Dr. Cody Wyles, #Dr. David Lott, #Dr. Saranya Wyles, #Dr. Shane Shapiro, #Mayo Clinic Center for Regenerative Biotherapeutics, #Orthobiologics, #Platelet-rich plasma


April 3, 2023

Pivoting toward a new strategy for fighting disease

By Susan Buckles Susan Buckles (@susanbuckles)

The Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023 opened today with a look at how biotherapeutics is shaping the future of medicine. “Our commitment to delivering new cures for unmet conditions is behind Mayo’s pivot to biomanufacturing,” says Julie Allickson, Ph.D., the Michael S. and Mary Sue Shannon Family Director of Mayo Clinic’s […]

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Tags: #Biomanufacturing, #biotherapeutics, #cell therapies, #Dr. Julie Allickson, #gene therapies, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine and Surgery


March 21, 2023

Advancing promising therapies through regulatory programs

By Susan Buckles Susan Buckles (@susanbuckles)

Learn about the latest regulatory programs designed to accelerate promising new therapies toward clinical care at the Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023. The event featuring nationally and internationally known speakers will be held April 3–5 at the Westin Kierland Resort and Spa in Scottsdale, Arizona. Peter Marks, M.D., Ph.D., director of […]

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Tags: #cell therapies, #Dr. Peter Marks, #Dr. Richard Hayden, #Food and Drug Administration, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine & Surgery, #Regenerative Medicine Advance Therapy


March 14, 2023

A twist of fate led to regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

A chance meeting on a student shuttle bus put Wenchun Qu, M.D., Ph.D., on a new  direction that years later would culminate in becoming the Jorge and Leslie Bacardi Associate Director of the Mayo Clinic Center for Regenerative Biotherapeutics in Florida. During a ride to the University of Southern California (USC) where Dr. Qu was […]

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Tags: #cell therapy, #Dr. Wenchun Qu, #gene therapy, #Mayo Clinic Center for Regenerative Biotherapeutics, #physical medicine & rehabilitation, #stem cell research


March 3, 2023

Early Mayo Clinic research finds hope in stem cell therapy for perianal fistulas in patients with Crohn’s disease

By Susan Buckles Susan Buckles (@susanbuckles)

A dissolvable plug delivered stem cell therapy with few side effects in patients with single tract perianal fistulas, Mayo Clinic researchers discovered. Perianal fistulas are painful tunnels between the intestine and the skin that often do not go away with standard medical or surgical care. People with Crohn’s disease or other inflammatory bowel conditions are […]

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February 21, 2023

Research prepares for Mayo’s first larynx transplant

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has refined a preclinical model that lays the foundation for its first-ever larynx transplant. The model assesses the unique immunosuppressive needs of vascular composite allograft (VCA) transplantation, a type of transplant that requires transferring many different types of tissues, such as muscle, blood vessels and nerves, along with the organ. A larynx transplant […]

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Tags: #Dr. David Lott, #laryngeal cancer, #laryngeal injury, #larynx transplant, #Mayo Clinic Center for Regenerative Biotherapeutics


February 16, 2023

CAR-T cell therapy co-inventor to keynote Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023

By Susan Buckles Susan Buckles (@susanbuckles)

Recognizing the potential of gene-modified T cells to transform medicine, researchers at the University of Pennsylvania have continued to innovate with clinical trials over the past two decades.  In a convergence of science, medicine and entrepreneurship, an industry collaborator brought the first breakthrough gene therapy for cancer to market in the U.S. in 2017 — […]

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Tags: #biologics, #CAR T-cell therapy, #Dr. Bruce Levine, #Dr. Richard Hayden, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine and Surgery


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