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January 19, 2023

Bioengineering vocal cords

By Susan Buckles Susan Buckles (@susanbuckles)

Tissue engineering techniques discovered at Mayo Clinic and Arizona State University created a humanlike vocal cord (fold) structure with the potential to produce a natural-sounding voice. The bioengineered scaffold mimics human vocal folds, with ability to vibrate and make sound. The study team reported the tissue-engineered vocal fold structure suggests potential for growing cells capable […]

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Tags: #Bioengineering, #Dr. David Lott, #Mayo Clinic Center for Regenerative Biotherapeutics, #Tissue engineering, #Vocal cord damage, #Vocal fold scarring


January 12, 2023

Reprogramming stem cells to heal disease

By Susan Buckles Susan Buckles (@susanbuckles)

At one point, Shinya Yamanaka, M.D., Ph.D., was so down and discouraged that he almost gave up his research into embryonic cells and their powerful potential to replace diseased cells. He was finding little interest among colleagues; funding was hard to come by; and research journals rejected his studies. Then, discovery of human embryonic cell […]

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Tags: #biologics, #Dr. Shinya Yamanaka, #induced pluripotent stem cells, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine and Surgery


January 5, 2023

Expanding regenerative biotherapeutics to new practice areas

By Susan Buckles Susan Buckles (@susanbuckles)

As a physician at the forefront of new cancer therapies, Yi Lin, M.D., Ph.D., understands the highs and lows that patients experience. Will the latest technologies slow or stop disease? If not, is this the last, best option? Dr. Lin, a hematologist, sees the need for a new class of drugs that provides different treatment […]

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Tags: #cancer immunotherapies, #CAR T-cell therapy, #Dr. Yi Lin, #gene therapy, #Mayo Clinic Center for Regenerative Biotherapeutics, #tissue engineeering


December 19, 2022

Aspiring to deliver new cures for complex conditions

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is building toward a future when biologics can cure cancer, kidney disease and diabetes. Mayo marks 2022 as a year of significant strides in accelerating science to make and deliver regenerative biotherapeutics. The goal is to offer new options, based on rigorous research in cell and gene therapies, for disorders with few available […]

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Tags: #biologics, #Biomanufacturing, #cell therapy, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Biotherapeutics, CAR-T cell therapy


December 12, 2022

Registration opens for Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023

By Susan Buckles Susan Buckles (@susanbuckles)

Learn the latest in regenerative biotherapeutics, biomanufacturing, regenerative medicine and application to clinical care at the Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023. Registration is now open for the event that will be held April 3–5 at the Westin Kierland Resort and Spa in Scottsdale, Arizona. Regenerative biotherapeutics is an emerging field in […]

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Tags: #Dr. Richard Hayden, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Symposium on Regenerative Medicine and Surgery, Dr. Bruce Levine, Dr. Harold Ott, Dr. Peter Marks, Dr. Raghu Kalluri, Dr. Shinya Yamanaka


November 30, 2022

Training scientists to rebuild health

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

Experts predict that regenerative medicine will transform clinical practice. A conservative estimate is that 20% of future medical and surgical solutions will involve regenerative solutions. Regenerative medicine shifts the focus of medicine from fighting disease to rebuilding health. Regenerative medicine could improve human health span — the number of disease-free years — so a person’s […]

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Tags: #Armin Garmany, #Dr. Isobel Scarisbrick, #Mayo Clinic Center for Regenerative Biotherapetics, #Mayo Clinic Graduate School of Biomedical Sciences, #Nathaniel Blackwell, #Regenerative Sciences Ph.D. track, #Shannon Gao


November 22, 2022

Mayo Clinic opens a second Regenerative Medicine Therapeutic Suites

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has opened the Regenerative Medicine Therapeutic Suites in Arizona for patients seeking enhanced care when standard procedures don’t meet their needs. The suites are an intersection of clinical practice, research and lab space where patients can have their cells processed on-site for immediate application to their condition. “It’s a whole new level of […]

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Tags: #bone marrow aspirate concentrate, #Dr. David Lott, #Dr. Shane Shapiro, #Mayo Clinic Center for Regenerative Biotherapeutics, #platelet rich plasma, #Regenerative Medicine Therapeutic Suites, #stromal vascular fraction cells


November 16, 2022

Engineering tissue to strengthen underdeveloped hearts

By Susan Buckles Susan Buckles (@susanbuckles)

Could cells taken from a small patch of skin become heart muscle and repair a rare congenital heart defect? It’s a scientific question that Timothy Nelson, M.D., Ph.D., and collaborators hope to answer for those born with an underdeveloped left heart chamber — a rare, complex condition known as hypoplastic left heart syndrome (HLHS). Discovering […]

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Tags: #cardiomyocytes, #congenital heart defects, #Dr. Timothy Nelson, #heart cells, #Hypoplastic Left Heart Syndrome, #Mayo Clinic Center for Regenerative Biotherapeutics, #Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome


November 9, 2022

Real-world evidence study of regenerative medicine and shoulder surgery

By Susan Buckles Susan Buckles (@susanbuckles)

Applying regenerative medicine to a common shoulder surgery could have an impact on the need for follow-up revision surgery in some patients, according to a Mayo Clinic study of real-world evidence. Mayo Clinic researchers analyzed the largest set of data available to determine if adding bone marrow aspirate concentrate to repaired tissue after standard rotator […]

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Tags: #bone marrow aspirate concentrate, #Center for Regenerative Biotherapeutics, #Dr. Bradley Schoch, #Dr. Christopher Camp, #Dr. Shane Shapiro, #Orthobiologics, #platelet rich plasma, #Regenerative biotherapeutics


October 19, 2022

Beating the odds for a transplant

By Susan Buckles Susan Buckles (@susanbuckles)

When the phone rang in the middle of a Sunday night news program, and the caller ID flashed Mayo Clinic, Dennis Pinkerton and his wife, Rhonda, knew it was a pivotal moment. The doctor on the line delivered news he thought he’d never hear. A pair of donor lungs — kept alive and breathing on […]

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Tags: #double lung transplant, #Dr. Ian Makey, #Dr. Jorge Mallea, #lung perfusion, #Mayo Clinic Center for Regenerative Biotherapeutics, Dennis Pinkerton, ex vivo lung perfusion system


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