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October 31, 2023

Paradigm shift in fistula care

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

From Mayo Clinic Alumni Magazine, 2023 issue 3 It started with a chance encounter in the Gonda Building on Mayo Clinic’s Rochester campus in 2013. Colorectal surgeon Eric Dozois, M.D., chair, Division of Colon and Rectal Surgery, ran into gastroenterologist William Faubion Jr., M.D., Division of Gastroenterology and Hepatology, and shared an idea. A fellow in colorectal […]

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Tags: #biomedical research, #Dr. Allan Dietz, #Dr. Eric Dozois, #Dr. William Faubion Jr., #Mayo Clinic Center for Regenerative Biotherapeutics, #Perianal fistula, #Stem cell therapy


October 27, 2023

Engineering stem cells to treat liver disease

By Susan Buckles Susan Buckles (@susanbuckles)

During clinical rotations in medical school, Kianna Nguyen encountered many patients with liver failure and was struck by a grim reality: Their only hope was a transplant. The shortage of donor organs and therapeutic options was at once frustrating and inspirational, triggering her research interest in cellular therapies for liver failure. “Research provides us with […]

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Tags: #Dr. Alexander Revzin, #embryonic stem cells, #Kianna Nguyen, #Liver failure, #Mayo Clinic Alix School of Mediciine, #Mayo Clinic Center for Regenerative Biotherapeutics, #Mayo Clinic Graduate School of Biomedical Sciences, #Stem cell encapsulation, #stem cells


October 11, 2023

Mayo Clinic prepares to biomanufacture a new CAR-T cell therapy for B-cell blood cancers        

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic research has developed a new type of chimeric antigen receptor-T cell therapy (CAR-T cell therapy) aimed at killing B-cell blood cancers that have returned and are no longer responding to treatment. This pioneering technology, designed and developed in the lab of Hong Qin, M.D., Ph.D., killed B-cell tumors grown in the laboratory and […]

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Tags: #B-cell blood cancers, #Biomanufacturing, #CAR T-cell therapy, #Dr. Hong Qin, #Dr. Julie Allickson, #Mayo Clinic Center for Regenerative Biotherapeutics


September 29, 2023

Training for a cellular battle against diabetes

By Susan Buckles Susan Buckles (@susanbuckles)

The need for better options in diabetes care inspires Kyle Knofczynski, a student in the Regenerative Sciences Ph.D. track at the Mayo Clinic Graduate School of Biomedical Sciences. Standard insulin replacement therapy has been a lifeline for many people with diabetes, but it doesn’t always sufficiently control blood glucose (sugar).  So Knofczynski dared to dream […]

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Tags: #Diabetes, #diabetes research, #Dr. Quinn Peterson, #Kyle Knofczynski, #Mayo Clinic Graduate School of Biomedical Sciences, #Regenerative Sciences Ph.D. track, #Type 1 diabetes


July 20, 2023

Could bioprinted skin uncover a new treatment for eczema?

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has developed its first 3D prototype of human skin bioprinted to model inflammatory skin disease. 3D bioprinting is a technology that mixes bioinks with living cells to print natural tissue-like structures in three dimensions. This new technology provides the most human-like skin model for studying inflammatory conditions such as atopic dermatitis — more […]

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Tags: #3D bioprinting, #Atopic dermatitis, #biomedical research, #cell therapy, #Center for Regenerative Biotherapeutics, #Dr. Saranya Wyles, #eczema, #medical research, #Skin 3D bioprinting


July 13, 2023

CAR-T cell therapy restores hope for leukemia patient

By Susan Buckles Susan Buckles (@susanbuckles)

Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says […]

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Tags: #biomedical research, #CAR T-cell therapy, #chronic lymphocytic leukemia, #Clinical trials, #Dr. Saad Kenderian, #Mayo Clinic Center Regenerative Biotherapeutics, #medical research


June 29, 2023

Mayo Clinic’s new four-pillar structure for biomanufacturing

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic’s Center for Regenerative Biotherapeutics is advancing a new biomanufacturing strategy focused on cellular therapies, gene and viral therapies, and tissue engineering for patients with rare and complex disorders. The goal is to accelerate promising discoveries to early stage clinical trials and then work with industry leaders to bring new healing options to patients. […]

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Tags: #Biomanufacturing, #Cameron Jones, #cell therapy, #Current Good Manufacturing Practice, #Dr. Cynthia Wilkins, #Mayo Clinic Center for Regenerative Biotherapeutics, #Snigda Rai, #Tony DeFusco


June 23, 2023

Mayo Clinic trains a new class of regenerative sciences students

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has selected five new students for one of the first-ever doctoral tracks in regenerative sciences. This is the third class admitted since the doctoral program began in 2020. Regenerative medicine and biotherapeutics are so new that very few academic medical centers have curricula to train the next generation of physicians and scientists to […]

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Tags: #Dr. Isobel Scarisbrick, #Fan Feng, #Isaiah Perez, #Kaleb Miles, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Graduate School of Biomedical Sciences, #Regenerative Sciences Ph.D. track, #Rylee Kopchak, #Sierra Mamernick


June 6, 2023

From Lift Off to Splash Down: An Update on Mayo Clinic Stem Cells in Space

By centerforregmedmc centerforregmedmc (@centerforregmedmc)

By Lynda De Widt Approximately 15 million people worldwide experience a stroke annually, according to the World Health Organization. Currently, stroke remains a top cause of death and disability in the world. Finding new therapies for stroke is important to Abba Zubair, M.D., Ph.D., a Mayo Clinic physician and scientist whose mother was stricken by a stroke when […]

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Tags: #Dr. Abba Zubair, #Mayo Clinic Center for Regenerative Biotherapeutics, #mesenchymal stem cells, #NASA award, #Stem cell therapy for stroke, #Stem cells in space


May 31, 2023

Mayo Clinic regenerative biotherapeutics showcased at international conference

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic physicians and scientists are sharing their expertise in regenerative biotherapeutics at a global conference in Paris this week. The International Society for Cell and Gene Therapy (ISCT) conference, Celebrating Progress, Building the Future, is bringing together roughly 2,000 people from around the world that work in industry, academia, government and health care. Together […]

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Tags: #Dr. Abba Zubair, #Dr. Allan Dietz, #Dr. Burcin Taner, #Dr. David Lott, #Dr. Julie Allickson, #Dr. Prathibha Varkey, #Dr. Richard Hayden, #Dr. Timothy Nelson, #Dr. Wenchun Qu, #Dr. Yi Lin, #International Society for Cell and Gene Therapy


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