News
February 1, 2021
Advancing cell-based regenerative therapy for heart failure
February is American Heart Month, a time to highlight innovative research that seeks to advance cellular therapy as a new option for restoring heart health. One of the latest discoveries in the Center for Regenerative Medicine and Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program established a way to engineer stem cells that activate regenerative […]
Tags: #Atta Behfar, #Biomanufacturing, #Cardiac regeneration, #cardiopoietic cells, #Mark Li, #Mayo Clinic Alix School of Medicine, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Graduate School of Biomedical Sciences
December 30, 2020
Pioneering living donor cartilage transplants
Mayo Clinic is poised to establish what is believed to be the first-ever living cartilage donor bank to provide a new regenerative option for healing common knee injuries. That donor bank will lay the foundation for living donor musculoskeletal tissue transplants — a first at Mayo Clinic and possibly in the world — to help […]
Tags: #cartilage defects, #Dr. Daniel Saris, #Dr. Mario Hevesi, #knee replacement surgery, #Mayo Clinic Center for Regenerative Medicine, #osteo chondral allograft transplant, Dr. Aaron Krych
November 3, 2020
3D brain models advance Alzheimer’s disease research at Mayo Clinic
A 3D model of brain organoids — “a minibrain in a dish” — mimics human brain structure and provides a new scientific strategy for exploring the pathology of Alzheimer’s disease, Mayo Clinic research discovered. The study, which was published in Nature Communications, finds that the minibrain — an induced pluripotent stem cell-derived cerebral organoid 3D […]
Tags: Alzheimer's disease, brain organoids, Guojun Bu, Mayo Clinic Center for Regenerative Medicine, pluripotent stem cells
October 29, 2020
Long-term safety, benefits of stem therapy for heart failure
The largest regenerative medicine clinical trial to date for heart failure finds stem cell therapy is safe over the long term and benefits patients with advanced left ventricular enlargement. This multinational research, co-led by Andre Terzic, M.D., Ph.D., director of Mayo Clinic’s Center for Regenerative Medicine, and published in ESC Heart Failure, offers guidance in […]
Tags: cardiac regeneration, cardiopoietic stem cells, CHART-1 Trial, Dr. Andre Terzic, heart disease, Mayo Clinic Center for Regeneration, stem cell therapy
October 22, 2020
Stem cell therapy for kidney damage repair
Mesenchymal stem cells derived from a person’s fat cells may help repair kidney damage caused by narrowing blood vessels, Mayo Clinic research has discovered. The research by Stephen Textor, M.D., and his team is published in Kidney International. Mayo Clinic Center for Regenerative Medicine and the National Institutes of Health supported this first-in-human study to […]
Tags: atherosclerosis, kidney disease, Mayo Clinic Center for Regenerative Medicine, mesenchymal stem cells, renovascular disease, Stem cell research, stem cell therapy, Stephen Textor
October 14, 2020
Mayo Clinic adopts regenerative medicine as field of academic rank
In a step that opens a whole new era of medical practice, Mayo Clinic has approved regenerative medicine as a field of academic rank. The decision will contribute to a new community of regenerative medicine scientists, physicians, engineers, administrators and health care staff equipped to advance new cures to address unmet patient needs. Regenerative medicine […]
Tags: Andre Terzic, Fredric Meyer, Mayo Clinic Center for Regenerative Medicine, regenerative medicine education, Robert Spinner
August 20, 2020
Stem cell research to improve hemodialysis
Stem cell therapy after angioplasty helps keep arteriovenous fistula blood vessels open, Mayo Clinic discovered in animal studies. An arteriovenous fistula is a passageway between an artery and a vein. This research, supported in part by the Mayo Clinic Center for Regenerative Medicine, provides a foundation on which someday patients with end stage renal disease, who […]
Tags: Angioplasty, arteriovenous fistula, chronic kidney disease, End stage renal disease, Hemodialysis, Mayo Clinic Center for Regenerative Medicine, Sanjay Misra, Stem cell research
June 18, 2020
Stem cells in space: interstellar research to improve regenerative therapies
Mayo Clinic research is reaching to the cosmos for answers on how to overcome hurdles in engineering human stem cells. Mesenchymal stem cells are adult stem cells with potential to unleash the body’s ability to heal diseased tissues and organs. However, growing or culturing stem cells in the laboratory is a slow process, and sometimes […]
Tags: Abba Zubair, International Space Station, Mayo Clinic Center for Regenerative Medicine, Mayo Clinic in Florida, Stem cell cultures, Stem cell research
March 12, 2020
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins […]
Tags: #Dr. Kent Arrell, #heart failury, cardiovascular disease, Cariopoietic stem cells, Dr. Andre Terzic, heart attack, Mayo Clinic Center for Regenerative Medicine, mesenchymal stem cells
January 16, 2020
Collaboration brings innovative regenerative therapies to babies with rare heart defect
By MayoRegMed 
A collaboration bringing together regional centers and advocacy groups to accelerate innovation and discovery is expanding, bringing clinical trials and expertise to more patients with Hypoplastic Left Heart Syndrome (HLHS) across the country. Led by Mayo Clinic’s Todd and Karen Wanek Family Program for HLHS, the collaboration began in 2017 and now has 10 members. […]
Tags: Congenital Heart Disease, Dr. Tim Nelson, HLHS, HLHS consortium, hypoplastic left heart syndrome