Cardiac regeneration
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: #Dr. Andre Terzic, #Dr. Satsuki Yamada, #Heart disease, #Mayo Clinic Center for Regenerative Medicine, Dr. Kent Arrell
December 1, 2021
A young father’s regenerative bridge to transplant
Mayo Clinic is pioneering and refining regenerative procedures that are a bridge to transplant. These procedures are providing new options for strengthening and rebuilding health while patients await the gift of life. Organ transplantation is one of the most serious and complex surgeries, but it also can dramatically restore a patient’s health and quality of […]
Tags: #Dr. Atta Behfar, #Dr. Sudhir Kushwaha, #Heart tranplant, #Intraaorta balloon pump, #Mayo Clinic Center for Regenerative Medicine
November 18, 2021
Boosting access for next-generation biotherapies
Enhanced access to regenerative treatments is needed so new healing solutions become broadly available in clinical care, according to Mayo Clinic research. Achieving validity, utility and mass customization would help realize the regenerative biotherapeutics potential, a Mayo Clinic study reports in the International Journal of Molecular Sciences. “Emerging individualized biotherapies call for on-demand solutions tailored […]
Tags: #cardiopoietic cells, #Dr. Andre Terzic, #Dr.. Satsuki Yamada, #Mayo Clinic Center for Regenerative Medicine, #stem cell research
August 5, 2021
The importance of individualized regenerative medicine
Individualized screening, guided by artificial intelligence (AI) and biomarkers, can optimize the transformative potential of regenerative medicine, according to a Mayo Clinic study. The paper, published in Biomarkers in Medicine, maintains that using new scientific tools to match the right biotherapeutics to the right patient ushers in the era of achieving tailored regenerative care. Conversely, […]
Tags: #artificial intelliegence, #Cardiac regeneration, #cardiopoietic cells, #Dr. Andre Terzic, #Dr. Satsuki Yamada, #genetic testing, #Mayo Clinic Center for Regenerative Medicine
June 24, 2021
Demystifying healing potential of stem cells
Mayo Clinic research has discovered proteins secreted by human stem cells that act as a “magic potion” to drive healing after a heart attack. The research uncovered that these cell-released regenerative particles harbor a pattern of functions mirrored in repair of the diseased heart, linking stem cell-transmitted information to the beneficial response of the recipient […]
Tags: #Cardiac regeneration, #cardiopoietic cells, #Dr. Andre Terzic, #Dr. Kent Arrell, #Heart attack, #myocardial infarction
May 20, 2021
Inspired to deliver new regenerative healing solutions
Growing up the son of a neurologist in China, Ao “Kevin” Shi, often would read his mother’s medical journals that featured Mayo Clinic research. Inspired, he pursued a career as a physician-scientist. Shi is now writing his own scholarly papers at Mayo Clinic that could transform care for people with peripheral vascular disease. Shi is […]
Tags: #Ao Shi, #Dr. Atta Behfar, #extra cellular vesicles, #Ischemic healing, #Ischemic wounds, #Mayo Clinic Center for Regenerative Medicine, #Regenerative Sciences Training Program, #Wound healing
February 1, 2021
Advancing cell-based regenerative therapy for heart failure
February is American Heart Month, a time to highlight innovative research that seeks to advance cellular therapy as a new option for restoring heart health. One of the latest discoveries in the Center for Regenerative Medicine and Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program established a way to engineer stem cells that activate regenerative […]
Tags: #Atta Behfar, #Biomanufacturing, #Cardiac regeneration, #cardiopoietic cells, #Mark Li, #Mayo Clinic Alix School of Medicine, #Mayo Clinic Center for Regenerative Medicine, #Mayo Clinic Graduate School of Biomedical Sciences
December 17, 2020
Diverse ways regenerative medicine is advancing health care
Regenerative medicine has contributed to patient care in 2020 more than ever before, bolstered by synergies in research, practice and education. Mayo Clinic’s Center for Regenerative Medicine is at the forefront of a biotherapy revolution in which health care advances from treating disease to restoring health. “The centrality of the body to regenerate itself is […]
Tags: #CAR-T cell therapy, #Dr. Andre Terzic, #Dr. Atta Behfar, #exosomes, #Mayo Clinic Center for Regenerative Medicine, #medical research, #stem cell research
October 29, 2020
Long-term safety, benefits of stem therapy for heart failure
The largest regenerative medicine clinical trial to date for heart failure finds stem cell therapy is safe over the long term and benefits patients with advanced left ventricular enlargement. This multinational research, co-led by Andre Terzic, M.D., Ph.D., director of Mayo Clinic’s Center for Regenerative Medicine, and published in ESC Heart Failure, offers guidance in […]
Tags: cardiac regeneration, cardiopoietic stem cells, CHART-1 Trial, Dr. Andre Terzic, heart disease, Mayo Clinic Center for Regeneration, stem cell therapy
March 12, 2020
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins […]
Tags: #Dr. Kent Arrell, #heart failury, cardiovascular disease, Cariopoietic stem cells, Dr. Andre Terzic, heart attack, Mayo Clinic Center for Regenerative Medicine, mesenchymal stem cells