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Nov 18, 2015

Meet the Researcher with Dr. Michael Yaszemski

By Center for Regenerative Medicine @centerforregmedmc
Michael Yaszemski, M.D., Ph.D., physician, orthopedic surgeon and engineer, wants to make it clear that the advances in orthopedic regenerative medicine are the product of teamwork. During his recent talk entitled "Mayo’s History of Military Research and Musculoskeletal Regenerative Medicine of Today," Dr. Yaszemski discussed the recent developments in regenerative orthopedic surgery and took the time to fully credit his team members for the hard work they've done. Since the advent of modern medicine there have been four eras of orthopedic surgery: resection, fusion, replacement and, now, regeneration. Resection was the process used in the very early days of surgery in which damaged joints were removed completely. This alleviated any pain but left patients unstable and unable to move freely. Next came fusion in which an injured joint was removed and the two bones fused together. Fusion gave patients stability but at the cost of mobility. In the 1950s replacement became the primary method thanks to the work done at Mayo Clinic under the guidance of Mark B. Coventry, M.D. During this era an injured joint was replaced with a metal or synthetic joint, which largely restored a patient's mobility. The issue with replacement is that the artificial joints will ultimately deteriorate, requiring repeat surgeries. [...]
Sep 22, 2015

HLHS Program Hosts Third Annual 'Feel the Beat' Event Oct. 17

By Center for Regenerative Medicine @centerforregmedmc
FEEL THE BEAT Saturday, October 17, 2015 10 a.m. - 3 p.m. Mayo Clinic Rochester, MN   'Feel the Beat' is a fun-filled day featuring new and exciting research taking place in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS), connecting families to others in the HLHS community and providing an opportunity to listen to and meet special guest speakers. This year the event will feature Chris Moir, M.D., Mayo Clinic pediatric surgeon who led a team to successfully separate 5-month-old conjoined twins; Ethan Bortnick, a 14-year-old piano prodigy; and Joslynn Jarrett-Skelton, author of Charlie the Courageous. The day also highlights how the HLHS program is making a difference and how the community can come together to increase awareness and support for our HLHS warriors. [...]
HLHS Program Hosts Third Annual 'Feel the Beat' Event Oct. 17
Sep 17, 2015

Uniting the Regenerative Medicine Community Through Global Collaboration

By Center for Regenerative Medicine @centerforregmedmc
The 2015 World Stem Cell Summit and RegMed Capital Conference will be held December 10-12 at the Hyatt Regency in Atlanta, Georgia, shaping the next year of progress in regenerative medicine. Mayo Clinic, the Georgia Center for Regenerative Engineering & Medicine (Georgia Tech, University of Georgia & Emory University), Kyoto University Institute for [...]
Uniting the Regenerative Medicine Community Through Global Collaboration
Sep 15, 2015

Nearing the Future of Regenerative Medicine

By Center for Regenerative Medicine @centerforregmedmc
Abba C. Zubair, M.D., Ph.D., medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida has traveled far in his life, moving from Nigeria to America in pursuit of science. Dr. Zubair spoke recently at Mayo Clinic in Rochester, explaining his plan to send an experiment beyond all borders to the International Space Station, a strategy that may accelerate the growth of human tissues and organs which currently require a substantial amount of time to develop due to gravity. The goal of Dr. Zubair's research — and regenerative medicine as a whole — is to boost the body's ability to heal itself. While many of us have the ability to recover from a cold or heal after an injury, the body has a limit to what it can do alone. For example, after a cut your skin heals within a few days. Other organs do not repair themselves as readily. But cells in the body once thought to be no longer able to divide (terminally differentiated) have been shown to be able to remodel and possess some ability to self-heal. Dr. Zubair and teams in the Mayo Clinic Center for Regenerative Medicine are studying how to enhance these self-healing processes. [...]
Aug 14, 2015

The Race is On - How Mayo Clinic is Using Regenerative Medicine Technology to Find a Cure for Diabetes

By Center for Regenerative Medicine @centerforregmedmc
This story first appeared in Mayo Clinic Magazine. For Caroline Schlehuber, an artificial pancreas might mean an end to finger pricks, blood reads and daily shots. Caroline can never escape her diabetes. It was there on her first day of school, at her first communion. It's there every Halloween, every Christmas, every vacation. She's pricked her finger eight to 10 times a day since she was 3 years old, including the six birthdays she's had since she was diagnosed. She understands that it wasn't her fault that her body turned on itself, that her immune system attacked her insulin-producing islet cells. To quote Caroline, "Diabetes doesn't care how cute you are. Diabetes doesn't care how well you play soccer. Diabetes doesn't care who your friends are or how much your family loves you." From the outside, her life looks perfectly normal. She plays soccer, swims with friends and goes to ballgames with her family. But in the background is the relentless hum of type 1 diabetes, with vigilant blood sugar surveillance and insulin adjustments. Her parents, Tom and Michelle Schlehuber, are thankful for the lifesaving medications and technologies that keep their daughter alive, but they pray for the day when Caroline isn't one missed reading away from the emergency room, when her life isn't dominated by glucose meters and insulin pumps. That day may be closer than they imagined. NEW POSSIBILITIES The road to discovery is long and riddled with ideas proven wrong. Researchers repeatedly see the most promising ideas fail when subjected to rigorous scientific method. The experience leaves most of them hesitant to use a certain four-letter word — "cure." Instead they use euphemisms like "advancing care" and "better treatments." [...]
The Race is On - How Mayo Clinic is Using Regenerative Medicine Technology to Find a Cure for Diabetes
Jul 31, 2015

Meet the Researcher: Abba Zubair, M.D., Ph.D., Talks Stem Cells in Space

By Center for Regenerative Medicine @centerforregmedmc
Abba C. Zubair, M.D., Ph.D., medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida will present "Growing Stem Cells in Space: Medicine’s Next Big thing?” All are welcome to the Research Information Center in Rochester, Minn. (Gonda Building, Lobby Level) Tuesday August 4, at 1:30 [...]
Meet the Researcher: Abba Zubair, M.D., Ph.D., Talks Stem Cells in Space
Jul 31, 2015

Researchers Test Bioartificial Liver Device to Treat Acute Liver Failure

By Center for Regenerative Medicine @centerforregmedmc
This story first appeared on the Mayo Clinic News Network. Approximately 30,000–40,000 people die from liver disease each year, according to the American Liver Foundation. For people who experience acute liver failure, the only proven treatment has been liver transplantation. Researchers at Mayo Clinic have developed and are testing an alternative [...]
Researchers Test Bioartificial Liver Device to Treat Acute Liver Failure
Jul 27, 2015

Human Cell Therapy Laboratory: Developing Drugs from the Patient, for the Patient

By Center for Regenerative Medicine @centerforregmedmc
This story originally appeared on the Mayo Medical Laboratories Blog. It’s almost a crime the outside world doesn’t know about the human clinical trials occurring at Mayo Clinic’s Human Cell Therapy Laboratory (HCTL) in Rochester. Currently, there are eleven (phase I) trials underway (or just finishing), investigating the use of [...]
Human Cell Therapy Laboratory: Developing Drugs from the Patient, for the Patient
Jul 15, 2015

Repairing Mitochondrial Disease

By Center for Regenerative Medicine @centerforregmedmc
A multidisciplinary team  has successfully  eliminated fatal mitochondrial DNA mutations in stem cells from patients with mitochondrial diseases. The study is published in the current issue of Nature as a collaboration between some of the top research institutions and Mayo Clinic's Center for Regenerative Medicine. Mitochondrial diseases are a particular [...]
Jul 10, 2015

New Lung Restoration Center to Bolster Lung Transplants

By Center for Regenerative Medicine @centerforregmedmc
Mayo Clinic, in collaboration with United Therapeutics Corporation, plans to change the landscape of lung transplantation with the construction of the new Lung Restoration Center in Jacksonville, Florida. The new center will use a process called ex vivo lung perfusion (EVLP) to revitalize donated lungs, allowing doctors to utilize organs [...]
New Lung Restoration Center to Bolster Lung Transplants
Jun 18, 2015

From Hypothesis to Bedside

By Center for Regenerative Medicine @centerforregmedmc
Medical research can be a challenging process, slowed by the complicated nature of translating research into treatment, but Mayo Clinic’s Nathan Staff, M.D., Ph.D., Assistant Professor of Neurology, has a plan to surmount these obstacles and streamline the research process. He and his colleagues detailed this plan in an issue [...]
From Hypothesis to Bedside
May 26, 2015

Regenerative Medicine to Repair Larynx

By Center for Regenerative Medicine @centerforregmedmc
David Lott, M.D. is working to establish Mayo Clinic as a leader in laryngeal transplantation utilizing regenerative medicine. He detailed his plan during a recent talk given at Mayo Clinic in Rochester. The larynx is the rigid organ situated in the neck responsible for protecting the airway, swallowing, and producing [...]
Apr 11, 2015

Regenerative Medicine Lecture Series - Rochester, Minn.

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Medical School and Center for Regenerative Medicine will host a regenerative medicine lecture series April 13-17. The lectures are part of the Mayo Medical School Regenerative Medicine Selective course, but are open to anyone who is interested in learning more about this exciting field. For more information, view [...]
Apr 10, 2015

Research Information Center to Host “Meet the Researcher” April 16

By Center for Regenerative Medicine @centerforregmedmc
David Lott, M.D. will present “Harnessing the Power of Regenerative Medicine for Head and Neck Reconstruction” in the Research Information Center in Rochester, Minn. (Gonda Building, Lobby Level) Thursday, April 16, at 2 p.m. Dr. Lott is dedicated to investigating disorders of the larynx (voice box) and airway. This includes [...]
Research Information Center to Host “Meet the Researcher” April 16
Jan 21, 2015

Seeing Hope: A Girl and Her Family Glimpse a Better Future

By Center for Regenerative Medicine @centerforregmedmc
From the pages of Mayo Clinic Magazine. The first thing the Arndts want you to know about them is their strong faith in God. They say it’s gotten them through some very tough times — mother Tara’s two bouts of cancer (one melanoma, one Hodgkin lymphoma); daughter Kelly’s head wound that sent her to the emergency room in an ambulance; and daughter Madison’s fight with H1N1 flu, which had killed several children in their home state of Minnesota that year. They knew their faith would see them through another trial two years ago, but Mom and Dad were worried. Doctors at Mayo Clinic noticed lesions on Madison’s eye, and the 11-year-old’s vision was getting worse. Her sight had never been great — she’d gotten her first eyeglasses at age 4, starting with a +3 prescription. Then at age 6, local doctors saw scarring on both eyes and referred her to Mayo. In the years between 6 and 11, Mayo Clinic worked with Madison and her parents, and Madison’s vision remained fairly stable. But these new lesions worried Mayo Clinic ophthalmologist Jose S. Pulido, M.D., as did the inflammation in her eyes. Mayo Clinic doctors placed a steroid implant, but soon Madison had headaches and blurry vision. Her eye pressures were extremely high at 43 (normal eye pressure ranges from 12 to 22), which Dr. Pulido relieved through a prescription of four eyedrops and a pill. And even though Dr. Pulido was doing everything he and colleagues could to control Madison’s symptoms, the future frightened her family. “We worried about the unknown,” Tara says. “That was the scary part — is she going to go blind? As a parent, you just want to know what’s wrong. Let’s get this fixed.” [...]
Seeing Hope: A Girl and Her Family Glimpse a Better Future
Dec 31, 2014

Mayo Clinic's Week at #WSCS14 in San Antonio

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Clinic Center for Regenerative Medicine used Mayo Clinic's social media networks to broadcast live to the public the latest from the 10th Annual World Stem Cell Summit. Below you will find a summary of content posted to Facebook, Google+, Twitter, YouTube and Flickr by Mayo Clinic and other attendees of the summit. This content is presented to you in a chronological order, broken down day by day, beginning with "Day 1 of 3" below. [...]
Mayo Clinic's Week at #WSCS14 in San Antonio
Nov 29, 2014

Uniting the Global Stem Cell Community

By Center for Regenerative Medicine @centerforregmedmc
Mayo Clinic Center for Regenerative Medicine to Co-Host the World Stem Cell Summit in San Antonio The World Stem Cell Summit, December 3-5 in San Antonio, unites and educates the global stem cell community. With more than 1,200 attendees from more than 40 countries, the annual World Stem Cell Summit’s interdisciplinary agenda explores disease updates, research directions, cell standardization, regulatory pathways, reimbursements, financing, venture capital and economic development. Throughout the week, the Mayo Clinic Center for Regenerative Medicine will use social media to connect using the hashtag #WSCS14. At the end of the week, we'll let the tweets, Google+ posts, Flickr photos, Facebook posts and YouTube videos tell the story. [...]
Uniting the Global Stem Cell Community
Nov 19, 2014

Mayo Scientist Receives American Heart Association 2014 Basic Research Prize

By Center for Regenerative Medicine @centerforregmedmc
The American Heart Association (AHA) awarded the 2014 Basic Research Prize to Andre Terzic, M.D., Ph.D., of Mayo Clinic. The award, presented at the annual meeting of the American Heart Association in Chicago, recognizes outstanding contributions to the advancement of cardiovascular science. Dr. Terzic was commended for pioneering applications of emerging [...]
Mayo Scientist Receives American Heart Association 2014 Basic Research Prize
Oct 27, 2014

Meet the Researchers – Drs. Anthony Windebank and Nathan Staff Discuss ALS Research at Mayo Clinic

By Center for Regenerative Medicine @centerforregmedmc
Anthony Windebank, M.D., and Nathan Staff, M.D., Ph.D., presented “ALS and Mayo Clinic – A Long History of Partnership in Research and Care” during Mayo Clinic Heritage Days in Rochester, Minn. Dr. Windebank, professor of neurology and deputy director for discovery in the Mayo Clinic Center for Regenerative Medicine, and Dr. [...]
Oct 15, 2014

Collaboration Highlight: Cardio3 BioSciences

By Center for Regenerative Medicine @centerforregmedmc
Since 2007, Mayo Clinic and Cardio3 BioSciences, a biotechnology company based in Mont-Saint-Guibert, Belgium, have collaborated to advance our knowledge of disease in order to provide new solutions for patients and innovative delivery of quality care in the area of cardiac regeneration. Cardiac regenerative medicine uses reparative tools to restore [...]
Collaboration Highlight: Cardio3 BioSciences
Oct 13, 2014

Register for "HLHS: Feel the Beat"

By Center for Regenerative Medicine @centerforregmedmc
“Feel the Beat” is an annual event that highlights Mayo Clinic’s commitment to transforming the practice of congenital heart disease with innovative regenerative strategies to prevent heart failure due to structural heart disease. This event brings together physicians, scientist, and children and families affected by severe heart defects, such as [...]
Register for
Sep 19, 2014

Center for Regenerative Medicine Forms Collaboration with National University Ireland Galway

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Clinic Center for Regenerative Medicine and colleagues at the National University Ireland (NUI) Galway have signed a formal memorandum of understanding (MOU) to pave the way for joint clinical trials using regenerative therapies. The MOU follows years of close collaboration with NUI Galway’s Regenerative Medicine Institute (REMEDI) and [...]
Center for Regenerative Medicine Forms Collaboration with National University Ireland Galway
Aug 21, 2014

"HLHS Feel the Beat" - Nov. 8, 2014

By Center for Regenerative Medicine @centerforregmedmc
  The second annual “HLHS Feel the Beat” will be held Saturday, November 8 at Mayo Clinic in Rochester, MInn. “HLHS Feel the Beat” is a fun-filled family event built around science, advocacy, families and patients. The Todd and Karen Wanek Family Program for HLHS will share the research being conducted [...]
Jul 30, 2014

Bacardi's Gift to Significantly Advance Mayo Clinic’s Regenerative Medicine Research

By Center for Regenerative Medicine @centerforregmedmc
Imagine a future in which a new lung is grown for a patient in need, using the patient’s own cellular material, or a day when an injection of replacement cells will enable a patient to self-heal damage in the brain, nerves or other tissues. Regenerative medicine is no longer science fiction, [...]
Bacardi's Gift to Significantly Advance Mayo Clinic’s Regenerative Medicine Research
Jul 18, 2014

Lung Regeneration in the Center for Regenerative Medicine

By Center for Regenerative Medicine @centerforregmedmc
Regenerative medicine has the potential to provide innovative new therapies for people with lung diseases, including chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, cystic fibrosis, pulmonary arterial hypertension and bronchiolitis obliterans. In their end stages, these diseases are today treated with medications or lung transplants, though there is an ongoing shortage of donor lungs that are [...]
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