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Feb 9, 2017

The Case for Stem Cell Treatments for ALS

By Center for Regenerative Medicine @centerforregmedmc
When nerve cells in the brain and the spinal cord stop working normally there is a noticeable change in muscle movement and activity. Motor neurons work with the brain to control muscle movement such as gripping and walking. These activities become increasingly difficult with the onset of amyotrophic lateral sclerosis [...]
The Case for Stem Cell Treatments for ALS
Jan 31, 2017

Mayo's Symposium on Regenerative Medicine and Surgery to Feature Latest Research

By Center for Regenerative Medicine @centerforregmedmc
It is not too late to register for the  Mayo Clinic Symposium on Regenerative Medicine and Surgery, Feb. 15-17, 2017 at the Westin Kierland Resort & Spa in Scottsdale, Ariz. Presentations will feature the latest in regenerative medicine and surgery, including general sessions in bioinformatics, ethics, project management, regulatory landscapes, technological [...]
Mayo's Symposium on Regenerative Medicine and Surgery  to Feature Latest Research
Jan 25, 2017

Four Mayo Clinic Investigators Receive Research Awards from ‘Regenerative Medicine Minnesota’

By Center for Regenerative Medicine @centerforregmedmc
Regenerative Medicine Minnesota recently announced the 2017 Regenerative Medicine Minnesota Research Awards. This year's research grants were aimed at developing and retaining early stage investigators. After review by 15 international reviewers, the top-scoring grants have been awarded funding. Four Mayo Clinic investigators were selected to receive awards. Mayo Clinic awardees include:   Patricia [...]
Four Mayo Clinic Investigators Receive Research Awards from ‘Regenerative Medicine Minnesota’
Jan 17, 2017

Regenerative Medicine Minnesota Grant Applications are Now Open

By Center for Regenerative Medicine @centerforregmedmc
Regenerative Medicine Minnesota recently announced the release of the 2017-2018 grant applications for Education Programs, Biotechnology/Biobusiness, and Clinical Care. Grant proposals are due Tuesday, February 14, 2017, by 5:00 PM CST. The Requests for Proposals (RFPs) and the application links can be found here. Questions regarding the application process can be [...]
Regenerative Medicine Minnesota Grant Applications are Now Open
Jan 10, 2017

Regenerative Medicine has Potential to Change How We Approach Cardiovascular Disease

By Center for Regenerative Medicine @centerforregmedmc
An article in Cardiology News describes the effort to bring regenerative medicine into clinical practice for cardiovascular disease. Although routine stem cell applications for cardiovascular disease are not yet available, current research spans the spectrum of heart diseases, deepening our knowledge base. This new knowledge is translating into a regenerative [...]
Regenerative Medicine has Potential to Change How We Approach Cardiovascular Disease
Dec 27, 2016

Mayo Clinic at the 2016 World Stem Cell Summit

By Center for Regenerative Medicine @centerforregmedmc
Medical research scientists, academics and clinicians mingled with entrepreneurs and patient advocates at the World Stem Cell Summit recently in West Palm Beach, Florida. In its fourth year as co-sponsor, Mayo Clinic Center for Regenerative Medicine sent a delegation to discuss the promise and the peril of the advancing science [...]
Mayo Clinic at the 2016 World Stem Cell Summit
Dec 23, 2016

Mayo Clinic Symposium on Regenerative Medicine and Surgery: Feb. 15-17, Scottsdale, Ariz.

By Center for Regenerative Medicine @centerforregmedmc
Registration is now open for the Mayo Clinic Symposium on Regenerative Medicine and Surgery, Feb. 15-17, 2017 at the Westin Kierland Resort & Spa in Scottsdale, Ariz. The event features presentations on the latest research in regenerative medicine and surgery and networking opportunities. Attendees are invited to submit abstracts for [...]
Dec 21, 2016

Mayo Clinic among World Stem Cell Summit poster prize winners

By Center for Regenerative Medicine @centerforregmedmc
The  2016 World Stem Cell Summit poster prize winners include Mayo Clinic's Amanda K. Golden, research medical writer, and Rosalie M. Sterner, M.D.-Ph.D. student. Posters were judged on contribution to the field of regenerative medicine, scientific method, creativity and communicative power. The World Stem Cell Summit poster forum covered a variety of regenerative medicine and stem cell research topics, including science and medicine, business, finance, regulation and law, ethics, policy and communications. Mayo Clinic winners were selected in two categories: ELSI (ethics, legal, social issues) and Science & Medicine. [...]
Mayo Clinic among World Stem Cell Summit poster prize winners
Dec 6, 2016

Mayo Clinic researchers test stem cell therapy to treat arthritis

By Center for Regenerative Medicine @centerforregmedmc
Researchers at Mayo Clinic’s campus in Florida have conducted the world’s first prospective, blinded and placebo-controlled clinical study to test the benefit of using bone marrow stem cells, a regenerative medicine therapy, to reduce arthritic pain and disability in knees. The researchers say such testing is needed because there are at least 600 stem cell clinics in the U.S. offering one form of stem cell therapy or another to an estimated 100,000-plus patients, who pay thousands of dollars, out of pocket, for the treatment, which has not undergone demanding clinical study. https://www.youtube.com/watch?v=3ZrOOxLT2mY The findings in The American Journal of Sports Medicine include an anomalous finding —patients not only had a dramatic improvement in the knee that received stem cells, but also in their other knee, which also had painful arthritis but received only a saline control injection. Each of the 25 patients enrolled in the study had two bad knees, but did not know which knee received the stem cells. [...]
Dec 2, 2016

Center for Regenerative Medicine to co-host World Stem Cell Summit Dec. 6-9

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Clinic Center for Regenerative Medicine is a co-sponsor of the 2016 World Stem Cell Summit. More than 1,200 attendees are expected at the 12th annual event in West Palm Beach, Florida. A delegation of administrators, researchers and clinical experts from Mayo Clinic will participate in featured presentations and panel discussions highlighting advances in discovery science, promising clinical trials and available therapies. Diverse topics to be covered include cardiovascular regeneration, restoring eyesight, and growing stem cells in a microgravity environment in space. Mayo Clinic experts also will be involved in panel discussions regarding education, consumer information and stem cell clinics. [...]
Center for Regenerative Medicine to co-host World Stem Cell Summit Dec. 6-9
Nov 29, 2016

Tissue Engineering and Regenerative Medicine Lecture

By Center for Regenerative Medicine @centerforregmedmc
Early in his career as a pediatric and transplant surgeon-scientist, Joseph P. Vacanti, M.D., was motivated by the problem of organ shortage for his tiny patients. It has led to a career long pursuit in solving the problem of organ availability for babies and young children. In an early case, [...]
Tissue Engineering and Regenerative Medicine Lecture
Nov 23, 2016

Healing from Within: The Promise of Regenerative Medicine

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Clinic Center for Regenerative Medicine, in partnership with Regenerative Medicine Minnesota, recently produced a patient-focused video called, “Healing from Within: The Promise of Regenerative Medicine.” The eight-minute educational video is funded by a patient care grant from Regenerative Medicine Minnesota. The video features  interviews with Mayo Clinic physicians [...]
Oct 21, 2016

National Academy of Medicine elects Mayo Clinic’s Michael Yaszemski, M.D., Ph.D.

By Center for Regenerative Medicine @centerforregmedmc
Michael J. Yaszemski, M.D., Ph.D., Mayo Clinic orthopedic surgeon and researcher, has been elected to the National Academy of Medicine. Selection is one of the highest honors in medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service. Dr. Yaszemski is one of two Mayo Clinic physicians to be elected this year. Andrea Cheville, M.D., physical medicine and rehabilitation researcher and director of the Cancer Rehabilitation Program at Mayo Clinic also was selected. “To have colleagues from distinct practice areas recognized in the same year is an incredible honor for them individually and for Mayo Clinic as a whole,” says John Noseworthy, M.D., president and CEO, Mayo Clinic. “Such recognition underscores the commitment of our physician-scientists in advancing research to address unmet patient needs, educating the next generation of physicians and scientists, and providing unparalleled care for patients and their families.” Dr. Yaszemski has a spine surgery practice at Mayo Clinic and routinely cares for patients who have skeletal defects that require reconstruction. His clinical practice includes spinal surgery and oncologic surgery of the spine, sacrum and pelvis. “Dr. Yaszemski is known as a strong clinical collaborator and he has built a differentiated surgical practice at Mayo Clinic. His team approach to complex spine surgery often includes colleagues in neurosurgery and is exemplary in the singular focus on the needs of the patient,” says Mark W. Pagnano, M.D., chair, Department of Orthopedic Surgery at Mayo Clinic. “Dr. Yaszemski’s surgical contributions and research advances continue to make a difference, not just for patients at Mayo Clinic but for patients nationwide and patients worldwide. His surgical skills are well-recognized amongst the nation’s spine surgeons.” Dr. Yaszemski is the director of the Tissue Engineering and Biomaterials Laboratory. His research is in the development of biodegradable scaffold polymers to support bone regeneration and spinal cord regeneration using tissue engineering strategies. He is a deputy director within Mayo Clinic’s Center for Regenerative Medicine. His research focus areas include: Biodegradable polymers Bone tissue engineering Spinal cord regeneration Nerve tissue engineering Sarcoma cell and molecular biology Dr. Yaszemski's long-term research goal is to change the way that many common debilitating, life-threatening musculoskeletal conditions are treated. The use of biodegradable polymers in bone tissue engineering will be significant to patients with spine instability or spinal cord injuries. [...]
National Academy of Medicine elects Mayo Clinic’s Michael Yaszemski, M.D., Ph.D.
Sep 29, 2016

Mayo Clinic Researchers Investigate Innovations in Heart Transplant

By Center for Regenerative Medicine @centerforregmedmc
Previously published in Mayo Clinic's research magazine, Discovery's Edge. As a science writer, I’m typically juggling a recorder, a note pad and a pen. Sometimes a camera. Today, the heart I held in my hand was warm and firm, red and healthy-looking. And beating. In my hand. Just an hour [...]
Mayo Clinic Researchers Investigate Innovations in Heart Transplant
Sep 7, 2016

HLHS Program Hosts Fourth Annual “Feel the Beat” Event Oct. 8

By Center for Regenerative Medicine @centerforregmedmc
The annual “Feel the Beat” event hosted by the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS) will be held on October 8 in Rochester, Minn.  “Feel the Beat” brings together clinicians, researchers, advocates, and families affected by a severe heart defect known as HLHS. The [...]
HLHS Program Hosts Fourth Annual “Feel the Beat” Event Oct. 8
Aug 31, 2016

Uniting the Regenerative Medicine Community

By Center for Regenerative Medicine @centerforregmedmc
The Mayo Clinic Center for Regenerative Medicine will co-host the 2016 World Stem Cell Summit  December 6-9 in West Palm Beach, FL. Organized by the Regenerative Medicine Foundation (RMF), the Summit forges collaborations to advance cell therapies, while creating a supportive environment of regulation, legislation, financing, reimbursement and patient advocacy. [...]
Uniting the Regenerative Medicine Community
Aug 26, 2016

New Strategies Could Make Laryngectomies a Thing of the Past

By Center for Regenerative Medicine @centerforregmedmc
Previously published in Mayo Clinic Magazine Today, about 60,000 Americans have had their larynx removed due to disease or trauma. These people are missing out on many of life’s little pleasures because the procedure’s resultant hole left them without a voice and created an opening directly into their lungs. A simple shower is dangerous as even the slightest amount of water in the lungs can be deadly. Bad weather can be lethal. Things that used to be a mere annoyance — such as a housefly — are now life-threatening. It’s not overstating it to say that danger lurks everywhere after a laryngectomy. And just at the time you need extra support, your ability to communicate is greatly impaired. A simple interaction with a store clerk is frustrating and can deliver looks of horror and pity. As an ear, nose and throat specialist at Mayo Clinic, David Lott, M.D., has seen laryngectomies impair too many lives. “I’m tired of seeing patients over and over and knowing there’s nothing to do,” he says. Some patients become so hopeless in the face of a laryngectomy that they forgo the procedure, opting for certain death over such deeply impaired living. Dr. Lott wants to restore hope for these people. And with the latest breakthroughs in transplant and regenerative medicine, he knows how. [...]
New Strategies Could Make Laryngectomies a Thing of the Past
Jul 5, 2016

Discovery's Edge: Hope For Healing With Regenerative Medicine

By Center for Regenerative Medicine @centerforregmedmc
Often perinatal fistulae resist treatment, both with medications and through treatment with a seton, a thread that is placed to promote drainage and healing. Currently standard therapies work less than half the time. Even when they do work, fistulae often return. Read the rest of the article on Discovery's Edge. ________________________ [...]
Discovery's Edge: Hope For Healing With Regenerative Medicine
Jun 28, 2016

Using Stem Cells to Try and Heal Baby Lucas’ Heart

By Center for Regenerative Medicine @centerforregmedmc
This story originally appeared on the In the Loop blog. ____________________ Last July, Jennifer Gutman told Toledo, Ohio’s 13abc Action News that the day doctors diagnosed her unborn son, Lucas, with hypoplastic left heart syndrome, also known as HLHS, was “the worst day of her life.” The diagnosis came during what Jennifer and [...]
Using Stem Cells to Try and Heal Baby Lucas’ Heart
Jun 24, 2016

Regenerative Medicine Offering New Treatment for Bronchopleural Fistulas

By Center for Regenerative Medicine @centerforregmedmc
When current treatment isn’t enough, patients at Mayo Clinic often are among the first to benefit from innovative therapies, new techniques and technologies. For the first time in human application, Mayo Clinic researchers successfully closed an open wound on the upper chest caused by postoperative complications of lung removal. The [...]
Regenerative Medicine Offering New Treatment for Bronchopleural Fistulas
Jun 13, 2016

Advancing Field of Transplantation: Lifetime Honor for Dr. Gonwa

By Center for Regenerative Medicine @centerforregmedmc
The American Society of Transplantation (AST) awarded its highest honor, the Lifetime Achievement Award, to Thomas Gonwa, M.D. at the recent American Transplant Congress in Boston. The Lifetime Achievement Award honors a senior investigator whose work has advanced the field of transplantation. Dr. Gonwa came to Mayo Clinic in 2001, after [...]
Advancing Field of Transplantation: Lifetime Honor for Dr. Gonwa
Jun 8, 2016

Promising Application for Stem Cells: Crohn's Complications

By Center for Regenerative Medicine @centerforregmedmc
New research at Mayo Clinic is bringing hope to hundreds of thousands of Crohn’s disease patients. Their extreme pain from complications is both physical and emotional and, for many, incurable. But, an innovation using the patient’s own stem cells seems to work extremely well in early testing. Eventually, researchers say, it [...]
Promising Application for Stem Cells: Crohn's Complications
Mar 14, 2016

Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer

By Center for Regenerative Medicine @centerforregmedmc
Researchers on Mayo Clinic’s Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent. The combination therapy worked in a laboratory study to stop lung adenocarcinoma associated with mutation of the KRAS gene. The study will be published in the March 14 issue of Cancer Cell. “If our approach works in KRAS-mediated lung adenocarcinoma, it may work in other KRAS-mediated cancers, such as pancreaticand colon cancers, as well as other cancer types,” says the study’s senior author, Alan P. Fields, Ph.D., a cancer biologist and the Monica Flynn Jacoby Professor of Cancer Research in the Department of Cancer Biology at Mayo Clinic in Florida. Based on this and other preclinical research from Dr. Fields’ team, Mayo Clinic is conducting early-phase clinical trials to test the effectiveness of auranofin alone and in targeted combinations in patients with KRAS-mediated lung adenocarcinoma, ovarian cancer, and another common lung cancer called lung squamous cell carcinoma. https://www.youtube.com/watch?v=W1LJHSn8zug [...]
Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer
Dec 8, 2015

Mayo Clinic Center for Regenerative Medicine to Co-Host World Stem Cell Summit in Atlanta

By Center for Regenerative Medicine @centerforregmedmc
The World Stem Cell Summit, December 10-12 in Atlanta, unites and educates the global stem cell community. With more than 1,200 attendees from more than 40 countries, the annual World Stem Cell Summit’s interdisciplinary agenda explores disease updates, research directions, cell standardization, regulatory pathways, reimbursements, financing, venture capital and economic development. Throughout the week, the Mayo Clinic Center for Regenerative Medicine will use social media to connect using the hashtag #WSCS15. At the end of the week, we'll let the tweets, Google+ posts, Flickr photos, Facebook posts and YouTube videos tell the story. [...]
Mayo Clinic Center for Regenerative Medicine to Co-Host World Stem Cell Summit in Atlanta
Nov 18, 2015

Meet the Researcher with Dr. Michael Yaszemski

By Center for Regenerative Medicine @centerforregmedmc
Michael Yaszemski, M.D., Ph.D., physician, orthopedic surgeon and engineer, wants to make it clear that the advances in orthopedic regenerative medicine are the product of teamwork. During his recent talk entitled "Mayo’s History of Military Research and Musculoskeletal Regenerative Medicine of Today," Dr. Yaszemski discussed the recent developments in regenerative orthopedic surgery and took the time to fully credit his team members for the hard work they've done. Since the advent of modern medicine there have been four eras of orthopedic surgery: resection, fusion, replacement and, now, regeneration. Resection was the process used in the very early days of surgery in which damaged joints were removed completely. This alleviated any pain but left patients unstable and unable to move freely. Next came fusion in which an injured joint was removed and the two bones fused together. Fusion gave patients stability but at the cost of mobility. In the 1950s replacement became the primary method thanks to the work done at Mayo Clinic under the guidance of Mark B. Coventry, M.D. During this era an injured joint was replaced with a metal or synthetic joint, which largely restored a patient's mobility. The issue with replacement is that the artificial joints will ultimately deteriorate, requiring repeat surgeries. [...]
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