March 6, 2020

Improving remyelination for spinal cord injury: Arthur Warrington, Ph.D.

By Jen Schutz

Mayo Clinic researchers are probing potential ways to unleash the human body’s ability to heal neurological disorders like spinal cord injuries or multiple sclerosis. Myelin is the protective covering that surrounds nerve fibers in the brain, optic nerves and spinal cord. Demyelination, or injury to the myelin, slows electrical signals between brain cells, resulting in loss of sensory and motor function. Through funding from Regenerative Medicine Minnesota, Mayo Clinic researcher Arthur Warrington, Ph.D., is investigating the ability of a human antibody to encourage the nervous system to regenerate its own myelin.

“As we age the myelin healing process takes longer, partly due to the aging immune system,” says Dr. Warrington. “We’re taking the concept of regenerative and therapeutic antibodies for multiple sclerosis (MS) and looking at whether that can be translated to rescue spinal cord injuries.”

A unique human antibody, discovered at Mayo Clinic, completed early stage clinical trial in patients with MS without any side effects. Because it was found to be safe in humans, researchers can now design studies for patients across the spectrum of neurological disease where remyelination would be of benefit, such as spinal cord injury, traumatic brain injury and stroke.

Tags: Arthur Warrington, Awards, MS, multiple sclerosis, Neurology, regenerative medicine, Research, spinal cord injury

My daughter had an SCI to T12 and lost all sensory and motor function to her legs. Could remyelation therapy help her?


I had sent in a comment for posting about my daughter having a SCI at T12level and asking if remyelation therapy could help her my contact information: Vic pozza phone 774 343 4898 if there is something remyelation can do for her. Thanks


I have written two comments previous. My. Name is Vic pozza. My email is

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